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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
megacolon +     
Absent Duct of Santorini 
Acrorenal Mandibular Syndrome 
Acrorenal Syndrome Recessive 
Anorectal Malformations +   
Barrett's esophagus +   
biliary atresia +   
choledochal cyst +   
Craniosynostosis, Anal Anomalies, and Porokeratosis 
Currarino syndrome  
diaphragmatic eventration +   
esophageal atresia +   
Hirschsprung's disease +   
Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
intestinal atresia +   
Meckel's diverticulum 
Pancreaticobiliary Maljunction 
toxic megacolon 
Volvulus Of Midgut  

Synonyms
Exact Synonyms: HSCR ;   HSCR1 ;   HSCR2 ;   HSCR3 ;   HSCR4 ;   HSCR5 ;   HSCR6 ;   HSCR7 ;   HSCR8 ;   HSCR9 ;   Hirschsprung disease ;   Hirschsprungs disease ;   MGC ;   aganglionic megacolon ;   colonic aganglionosis ;   congenital intestinal aganglionosis ;   congenital megacolon ;   macrocolon ;   pelvirectal achalasia ;   rectosigmoid aganglionosis ;   rectosigmoid colon aganglionosis ;   total colonic aganglionosis
Narrow Synonyms: Hirschsprung disease, dominant ;   Hirschsprung disease, recessive
Related Synonyms: Hirschsprung Disease, Susceptibility to, 1 ;   Hirschsprung Disease, Susceptibility to, 2 ;   Hirschsprung Disease, Susceptibility to, 3 ;   Hirschsprung Disease, Susceptibility to, 4 ;   Hirschsprung Disease, Susceptibility to, 5 ;   Hirschsprung Disease, Susceptibility to, 6 ;   Hirschsprung Disease, Susceptibility to, 7 ;   Hirschsprung Disease, Susceptibility to, 8 ;   Hirschsprung Disease, Susceptibility to, 9 ;   Hirschsprung disease, protection against
Primary IDs: MESH:D006627
Alternate IDs: OMIM:142623 ;   OMIM:600155 ;   OMIM:600156 ;   OMIM:606874 ;   OMIM:606875 ;   OMIM:608462 ;   OMIM:611644 ;   OMIM:613711 ;   OMIM:613712 ;   RDO:0000841
Xrefs: GARD:6660 ;   ICD10CM:Q43.1 ;   NCI:C34700 ;   OMIM:PS142623 ;   ORDO:388
Definition Sources: http://digestive.niddk.nih.gov/ddiseases/pubs/hirschsprungs_ez/ "DO", http://en.wikipedia.org/wiki/Hirschsprung%27s_disease "DO", http://www.nlm.nih.gov/medlineplus/ency/article/001140.htm "DO", http://www.uptodate.com/contents/congenital-aganglionic-megacolon-hirschsprung-disease "DO", MESH:D006627

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.