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Ontology Browser

Term:
Creutzfeldt-Jakob disease (DOID:11949)
Annotations: Rat: (20) Mouse: (19) Human: (22) Chinchilla: (13) Bonobo: (18) Dog: (16) Squirrel: (13) Pig: (15)
Parent Terms Term With Siblings Child Terms
dementia +     
prion disease +     
AIDS Dementia Complex  
Alzheimer's disease +   
amyotrophic lateral sclerosis-parkinsonism/dementia complex 1  
Ataxia with Myoclonic Epilepsy and Presenile Dementia 
Cerebral Amyloidosis with Spongiform Encephalopathy +   
chronic wasting disease 
Creutzfeldt-Jakob disease +   
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
deafness-dystonia-optic neuronopathy syndrome  
Dementia/Parkinsonism with Non-Alzheimer Amyloid Plaques 
Diffuse Neurofibrillary Tangles with Calcification 
fatal familial insomnia  
Frontotemporal Lobar Degeneration +   
Huntington's disease +   
Huntington's disease-like 1  
Huntington's disease-like 2  
ITM2B-related cerebral amyloid angiopathy 2  
juvenile amyotrophic lateral sclerosis with dementia 
Kluver-Bucy syndrome +  
Kohlschutter-Tonz syndrome  
kuru  
Lewy body dementia +   
MAST syndrome  
Motor Neuron Disease with Dementia and Ophthalmoplegia 
Presenile Dementia, Kraepelin Type 
Primary Progressive Aphasia +   
scrapie  
Spastic Paraplegia, Optic Atrophy, and Dementia 
Spongiform Encephalopathy with Neuropsychiatric Features  
variant Creutzfeldt-Jakob disease +  
vascular dementia +   
Wright Dyck Syndrome 

Synonyms
Exact Synonyms: CJD ;   Creutzfeldt Jacob Disease ;   Creutzfeldt Jacob syndrome ;   Creutzfeldt-Jakob syndrome ;   Familial Creutzfeldt-Jakob Diseases ;   New Variant Creutzfeldt Jakob Disease ;   Transmissible virus dementia ;   V CJD (variant Creutzfeldt Jakob disease) ;   familial Creutzfeldt Jakob disease ;   subacute spongiform encephalopathies ;   subacute spongiform encephalopathy
Narrow Synonyms: CREUTZFELDT-JAKOB DISEASE, FAMILIAL CREUTZFELDT-JAKOB DISEASE, SPORADIC ;   CREUTZFELDT-JAKOB DISEASE, HEIDENHAIN VARIANT ;   CREUTZFELDT-JAKOB DISEASE, VARIANT ;   sCJD ;   vCJD
Related Synonyms: Protection Against Creutzfeldt-Jakob Disease
Primary IDs: MESH:D007562 ;   RDO:0004437
Alternate IDs: OMIM:123400
Xrefs: GARD:6956 ;   ICD10CM:A81.0 ;   ICD10CM:A81.00 ;   ICD9CM:046.1 ;   NCI:C26802
Definition Sources: MESH:D007562

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.