Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
synucleinopathy +     
Dementia/Parkinsonism with Non-Alzheimer Amyloid Plaques 
Lewy body dementia +   
multiple system atrophy +   
Parkinson's disease +   
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Parkinsonism with Spasticity, X-Linked  
Perry syndrome  
secondary Parkinson disease +   

Synonyms
Exact Synonyms: Idiopathic Parkinson's Disease ;   Lewy Body Parkinson Disease ;   Lewy Body Parkinson's Disease ;   PARKINSON DISEASE, DOMINANT/RECESSIVE ;   PARKINSON'S DISEASE, DOMINANT ;   PARKINSON'S DISEASE, DOMINANT/RECESSIVE ;   PARKINSON'S DISEASE, RECESSIVE ;   PARKINSON'S DISEASE, RESISTANCE TO ;   Paralysis Agitans ;   Parkinson Disease ;   idiopathic Parkinson disease ;   primary parkinsonism
Narrow Synonyms: PARKINSON DISEASE, DOMINANT ;   PARKINSON DISEASE, RECESSIVE ;   PARKINSONISM/MELAS OVERLAP SYNDROME ;   familial Parkinson's disease
Related Synonyms: DOPAMINE BETA-HYDROXYLASE ACTIVITY, PLASMA ;   PARKINSON DISEASE, RESISTANCE TO ;   Parkinson Disease, Susceptibility To ;   Parkinson's disease, susceptibility to
Primary IDs: MESH:D010300
Alternate IDs: RDO:0002963
Xrefs: GARD:10251 ;   OMIM:PS168600 ;   ORDO:2828
Definition Sources: MESH:D010300, http://en.wikipedia.org/wiki/Parkinson%27s_disease

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.