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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
aceruloplasminemia  
agenesis of the corpus callosum with peripheral neuropathy  
BRAIN ABNORMALITIES, NEURODEGENERATION, AND DYSOSTEOSCLEROSIS  
Charcot-Marie-Tooth disease +   
Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy  
Childhood-Onset Neurodegeneration with Brain Atrophy  
Childhood-Onset Neurodegeneration with Cerebellar Atrophy  
chronic fatigue syndrome  
Chronic Traumatic Encephalopathy 
Cyclic Vomiting Syndrome with Neuromuscular Disease 
Cyprus Facial Neuromusculoskeletal Syndrome 
demyelinating disease +   
eye degenerative disease +   
eyelid degenerative disease +  
Feigenbaum Bergeron Richardson Syndrome 
FINCA Syndrome  
GSD IV, Neuromuscular Form, Adult, with Isolated Myopathy 
GSD IV, Neuromuscular Form, Childhood  
GSD IV, Neuromuscular Form, Congenital  
GSD IV, Neuromuscular Form, Fatal Perinatal  
hereditary ataxia +   
Huntington's disease-like 2  
Idiopathic Basal Ganglia Calcification 1  
Idiopathic Basal Ganglia Calcification 6  
Idiopathic Basal Ganglia Calcification 7  
LEUKOENCEPHALOPATHY, DEVELOPMENTAL DELAY, AND EPISODIC NEUROLOGIC REGRESSION SYNDROME  
locked-in syndrome 
motor neuron disease +   
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
multiple system atrophy +   
muscular disease +   
myoclonic cerebellar dyssynergia +  
Nervous System Heredodegenerative Disorders +   
neurodegeneration with brain iron accumulation +   
NEURODEGENERATION, EARLY-ONSET, WITH CHOREOATHETOID MOVEMENTS AND MICROCYTIC ANEMIA  
NEURODEVELOPMENTAL DISORDER WITH EPILEPSY, SPASTICITY, AND BRAIN ATROPHY  
neuromuscular junction disease +   
Neuromuscular Oculoauditory Syndrome  
Neuronal Intranuclear Inclusion Disease  
NEUROPATHY, CONGENITAL HYPOMYELINATING, 2  
NEUROPATHY, CONGENITAL HYPOMYELINATING, 3  
olivopontocerebellar atrophy +   
optic nerve astrocytoma +  
Paraneoplastic Syndromes, Nervous System +   
PEHO syndrome  
Pick's disease  
plexopathy 
pontocerebellar hypoplasia +   
postpoliomyelitis syndrome 
primary cerebellar degeneration +   
prion disease +   
Radiation Sensitivity Chromosome Instability Syndrome, Autosomal Dominant 
Recurrent Metabolic Crises with Variable Encephalomyopathic Features and Neurologic Regression  
secondary Parkinson disease +   
Spastic Pseudosclerosis 
stress-induced childhood-onset neurodegeneration with variable ataxia and seizures  
Subacute Combined Degeneration  
synucleinopathy +   
tauopathy +   
TDP-43 Proteinopathies +   

Synonyms
Exact Synonyms: Lower Motor Neuron Disease ;   Motor Neuron Diseases ;   Motor System Disease ;   Motor System Diseases ;   Secondary Motor Neuron Disease ;   familial motor neuron disease ;   upper motor neuron disease
Narrow Synonyms: MADRAS MOTOR NEURON DISEASE
Primary IDs: MESH:D016472
Alternate IDs: RDO:0002003
Xrefs: ICD10CM:G12.20 ;   ICD9CM:335.2
Definition Sources: http://en.wikipedia.org/wiki/Motor_neuron_disease "DO", MESH:D016472

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.