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Ontology Browser

striatonigral degeneration (DOID:4751)
Annotations: Rat: (6) Mouse: (6) Human: (7) Chinchilla: (4) Bonobo: (4) Dog: (6) Squirrel: (4) Pig: (6)
Parent Terms Term With Siblings Child Terms
Multiple System Atrophy (MSA) with Orthostatic Hypotension 
olivopontocerebellar atrophy +   
Shy-Drager Syndrome  
striatonigral degeneration +   
A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)

Exact Synonyms: Striatonigral Atrophy ;   striatonigral atrophies ;   striatonigral degenerations
Narrow Synonyms: Striatal Necrosis, Bilateral, with Dystonia
Primary IDs: MESH:D020955
Alternate IDs: RDO:0007452
Xrefs: NCI:C125695 ;   OMIM:PS271930
Definition Sources: MESH:D020955

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.