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Ontology Browser

Shy-Drager Syndrome (DOID:9002322)
Annotations: Rat: (3) Mouse: (3) Human: (3) Chinchilla: (2) Bonobo: (2) Dog: (3) Squirrel: (2) Pig: (3)
Parent Terms Term With Siblings Child Terms
Hypotension +     
Multiple System Atrophy (MSA) with Orthostatic Hypotension 
olivopontocerebellar atrophy +   
Orthostatic Hypotension +   
Post-Exercise Hypotension 
Shy-Drager Syndrome  
A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536)
striatonigral degeneration +   

Exact Synonyms: Dysautonomia Orthostatic Hypotension Syndrome ;   Dysautonomic Orthostatic Hypotension ;   Dysautonomic Orthostatic Hypotensions ;   Idiopathic Orthostatic Hypotension, Shy Drager Type ;   Progressive Autonomic Failure ;   dysautonomia-orthostatic hypotension syndromes ;   progressive autonomic failures
Primary IDs: MESH:D012791
Alternate IDs: RDO:0006570
Definition Sources: MESH:D012791

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.