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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
DNA damage checkpoint +   
A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.
DNA damage induced protein phosphorylation  
DNA damage response, detection of DNA damage +   
DNA repair +   
DNA replication checkpoint +   
histone H3-K56 acetylation in response to DNA damage 
histone H4 acetylation involved in response to DNA damage stimulus +  
intrinsic apoptotic signaling pathway in response to DNA damage +   
meiotic DNA integrity checkpoint +   
mitotic DNA integrity checkpoint +   
negative regulation of response to DNA damage stimulus +   
positive regulation of response to DNA damage stimulus +   
regulation of response to DNA damage stimulus +   
regulation of transcription from RNA polymerase II promoter in response to DNA damage  
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage +   
signal transduction in response to DNA damage +   
signal transduction involved in DNA integrity checkpoint +   
SOS response 
telomere maintenance in response to DNA damage +   

Synonyms
Narrow Synonyms: DNA damage response, signal transduction resulting in cell cycle arrest
Xrefs: Wikipedia:DNA_damage_checkpoint ;   Wikipedia:Postreplication_checkpoint
Definition Sources: GOC:mtg_cell_cycle

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.