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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
peptidase complex +     
SAGA-type complex +     
endopeptidase complex +   
glutathione hydrolase complex 
H-gal-GP complex 
m-AAA complex  
PCAF complex  
PNGase complex 
SAGA complex  
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8.
serine-type peptidase complex +   
signal peptidase complex  
SLIK (SAGA-like) complex  
STAGA complex  
transcription factor TFTC complex  

Synonyms
Exact Synonyms: Spt-Ada-Gcn5-acetyltransferase complex
Definition Sources: PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.