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Ontology Browser

Term:
tRNA 3'-terminal CCA addition (GO:0001680)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1)
Parent Terms Term With Siblings Child Terms
mitochondrial tRNA 3'-end processing  
tRNA 3'-terminal CCA addition  
Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.
tRNA 3'-trailer cleavage +   

Synonyms
Exact Synonyms: CCA-adding enzyme activity ;   CCA-adding enzyme, tRNA adenylyltransferase, tRNA cytidylyltransferase, tRNA CCA-pyrophosphorylase activity ;   ribonucleic cytidylic cytidylic adenylic pyrophosphorylase activity
Narrow Synonyms: CTP:tRNA cytidylyltransferase activity ;   ribonucleic cytidylyltransferase activity ;   tRNA cytidylyltransferase activity ;   transfer RNA adenylyltransferase activity ;   transfer ribonucleate adenyltransferase activity ;   transfer ribonucleate adenylyltransferase activity ;   transfer ribonucleate cytidylyltransferase activity
Broad Synonyms: ATP(CTP)-tRNA nucleotidyltransferase activity ;   CCA tRNA nucleotidyltransferase activity ;   tRNA adenylyl(cytidylyl)transferase activity ;   tRNA-nucleotidyltransferase activity ;   transfer ribonucleate nucleotidyltransferase activity ;   transfer ribonucleic acid nucleotidyl transferase activity ;   transfer ribonucleic-terminal trinucleotide nucleotidyltransferase activity ;   transfer-RNA nucleotidyltransferase activity
Related Synonyms: -C-C-A pyrophosphorylase activity ;   tRNA CCA-diphosphorylase activity ;   transfer ribonucleic adenylyl (cytidylyl) transferase activity
Xrefs: KEGG_REACTION:R09382 ;   MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN
Definition Sources: EC:2.7.7.72, GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.