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Ontology Browser

Term:
antibody-dependent cellular cytotoxicity (GO:0001788)
Annotations: Rat: (4) Mouse: (5) Human: (2) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1)
Parent Terms Term With Siblings Child Terms
antibody-dependent cellular cytotoxicity +   
Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
microglial cell mediated cytotoxicity +   
natural killer cell mediated cytotoxicity +   
negative regulation of leukocyte mediated cytotoxicity +   
negative regulation of type IIa hypersensitivity +   
neutrophil mediated cytotoxicity +   
positive regulation of leukocyte mediated cytotoxicity +   
positive regulation of type IIa hypersensitivity +   
regulation of leukocyte mediated cytotoxicity +   
regulation of type IIa hypersensitivity +   
T cell mediated cytotoxicity +   

Synonyms
Exact Synonyms: ADCC ;   antibody dependent cell death ;   antibody-dependent cell killing ;   type VI hypersensitivity
Xrefs: Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity ;   Wikipedia:Antibody-dependent_cellular_cytotoxicity
Definition Sources: GOC:pr, ISBN:0781735149, PMID:11677095, PMID:9581795

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.