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Ontology Browser

Term:
epithelial to mesenchymal transition (GO:0001837)
Annotations: Rat: (141) Mouse: (136) Human: (136) Chinchilla: (131) Bonobo: (131) Dog: (72) Squirrel: (3) Pig: (88)
Parent Terms Term With Siblings Child Terms
cardiac endothelial to mesenchymal transition +   
epithelial to mesenchymal transition +   
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
mesenchymal cell development +   
mesenchymal cell differentiation involved in bone development  
mesenchymal cell differentiation involved in lung development  
mesenchymal cell differentiation involved in mammary gland development 
mesenchymal cell differentiation involved in renal system development +   
mesenchymal cell differentiation involved in salivary gland development 
mesenchymal cell fate commitment 
neural crest cell differentiation +   

Synonyms
Exact Synonyms: EMT ;   epithelial-mesenchymal transition ;   mesenchymal cell differentiation from epithelial cell
Definition Sources: GOC:dph, PMID:14701881

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.