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Ontology Browser

Term:
type II hypersensitivity (GO:0002445)
Annotations: Rat: (6) Mouse: (9) Human: (4) Chinchilla: (3) Bonobo: (3) Dog: (2) Squirrel: (0) Pig: (2)
Parent Terms Term With Siblings Child Terms
basophil mediated immunity +   
eosinophil mediated immunity +   
humoral immune response mediated by circulating immunoglobulin +   
immune complex formation  
immunoglobulin production involved in immunoglobulin mediated immune response +   
immunoglobulin-mediated neutralization 
mast cell mediated immunity +   
microglial cell mediated cytotoxicity +   
myeloid dendritic cell cytokine production +   
negative regulation of hypersensitivity +   
negative regulation of immunoglobulin mediated immune response +   
negative regulation of myeloid leukocyte mediated immunity +   
neutrophil mediated immunity +   
positive regulation of hypersensitivity +   
positive regulation of immunoglobulin mediated immune response +   
positive regulation of myeloid leukocyte mediated immunity +   
regulation of hypersensitivity +   
regulation of immunoglobulin mediated immune response +   
regulation of myeloid leukocyte mediated immunity +   
type I hypersensitivity +   
type II hypersensitivity +   
An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.
type III hypersensitivity +   
type IV hypersensitivity +   

Synonyms
Xrefs: Wikipedia:Type_II_hypersensitivity
Definition Sources: GOC:add, ISBN:0781735149

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.