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Ontology Browser

Term:
sphingosine-1-phosphate receptor signaling pathway (GO:0003376)
Annotations: Rat: (9) Mouse: (5) Human: (10) Chinchilla: (10) Bonobo: (10) Dog: (8) Squirrel: (0) Pig: (8)
Parent Terms Term With Siblings Child Terms
adrenergic receptor signaling pathway +   
angiotensin-activated signaling pathway +   
apelin receptor signaling pathway  
bombesin receptor signaling pathway  
calcitonin family receptor signaling pathway +   
cannabinoid signaling pathway +   
cholecystokinin signaling pathway +   
complement component C5a signaling pathway  
endothelin receptor signaling pathway +   
follicle-stimulating hormone signaling pathway  
G protein-coupled acetylcholine receptor signaling pathway +   
G protein-coupled glutamate receptor signaling pathway +   
G protein-coupled purinergic receptor signaling pathway +   
G protein-coupled receptor signaling in absence of ligand 
G protein-coupled receptor signaling pathway involved in dauer larval development 
G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 
G protein-coupled receptor signaling pathway involved in heart process +   
G protein-coupled receptor signaling pathway involved in social behavior 
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger +   
G protein-coupled serotonin receptor signaling pathway +   
gamma-aminobutyric acid signaling pathway  
gastric inhibitory peptide signaling pathway  
ion channel modulating, G protein-coupled receptor signaling pathway +  
leukotriene signaling pathway  
luteinizing hormone signaling pathway +   
negative regulation of G protein-coupled receptor signaling pathway +   
negative regulation of sphingolipid mediated signaling pathway 
neuropeptide signaling pathway +   
octopamine or tyramine signaling pathway +  
opioid receptor signaling pathway +   
phospholipase C-activating G protein-coupled receptor signaling pathway +   
phospholipase C-inhibiting G protein-coupled receptor signaling pathway  
phospholipase D-activating G protein-coupled receptor signaling pathway  
positive regulation of G protein-coupled receptor signaling pathway +   
positive regulation of sphingolipid mediated signaling pathway  
protein kinase C-activating G protein-coupled receptor signaling pathway  
regulation of G protein-coupled receptor signaling pathway +   
regulation of sphingolipid mediated signaling pathway +   
rhodopsin mediated signaling pathway +   
somatostatin receptor signaling pathway +   
sphingosine-1-phosphate receptor signaling pathway  
A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
tachykinin receptor signaling pathway +   
thrombin-activated receptor signaling pathway +   
thromboxane A2 signaling pathway  
thyroid-stimulating hormone signaling pathway  

Synonyms
Exact Synonyms: S1P receptor signaling pathway ;   S1P-activated G-protein coupled receptor signaling pathway ;   S1P-activated GPCR signaling pathway ;   S1P-stimulated signal transduction pathway ;   sphingolipid signalling pathway
Broad Synonyms: sphingolipid signaling pathway
Related Synonyms: S1P signaling pathway
Alternate IDs: GO:0001789
Definition Sources: GOC:ascb_2009, GOC:signaling, PMID:14592418, PMID:22001186, Reactome:R-HSA-419428

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.