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Ontology Browser

Term:
DNA-binding transcription factor activity (GO:0003700)
Annotations: Rat: (1073) Mouse: (1028) Human: (1341) Chinchilla: (1153) Bonobo: (1215) Dog: (828) Squirrel: (40) Pig: (921)
Parent Terms Term With Siblings Child Terms
anti-sigma factor antagonist activity 
DNA-binding transcription factor activity +   
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
general transcription initiation factor activity +   
RNA-binding transcription regulator activity 
sigma factor activity 
transcription antitermination factor activity, DNA binding 
transcription antitermination factor activity, RNA binding 
transcription coregulator activity +   
transcription elongation regulator activity  
transcription regulator recruiting activity +   

Synonyms
Exact Synonyms: gene-specific transcription factor activity ;   sequence-specific DNA binding transcription factor activity
Narrow Synonyms: bacterial-type DNA binding transcription factor activity ;   bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity ;   bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity ;   metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity ;   metal ion regulated sequence-specific DNA binding transcription factor activity ;   nucleic acid binding transcription factor activity ;   sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity ;   transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding ;   transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding ;   transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding
Broad Synonyms: transcription factor activity
Alternate IDs: GO:0000130 ;   GO:0001071 ;   GO:0001130 ;   GO:0001131 ;   GO:0001151 ;   GO:0001199 ;   GO:0001204
Definition Sources: GOC:txnOH-2018

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.