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Term:
peptidyl-prolyl cis-trans isomerase activity (GO:0003755)
Annotations: Rat: (43) Mouse: (37) Human: (46) Chinchilla: (23) Bonobo: (23) Dog: (45) Squirrel: (23) Pig: (38)
Parent Terms Term With Siblings Child Terms
2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity 
4-hydroxyphenylacetaldehyde-oxime isomerase activity 
9,15,9'-tri-cis-zeta-carotene isomerase activity 
[acyl-carrier-protein] phosphodiesterase activity 
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase 
[protein-PII] uridylyltransferase activity 
alpha-1,4-glucan-protein synthase (ADP-forming) activity 
biotin-protein ligase activity +   
carotenoid isomerase activity 
catalytic activity, acting on a glycoprotein +   
cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity 
deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity 
dihydrolipoyllysine-residue acetyltransferase activity  
dihydrolipoyllysine-residue succinyltransferase activity  
farnesol 2-isomerase activity 
furylfuramide isomerase activity 
linoleate isomerase activity 
lipoate-protein ligase activity  
maleate isomerase activity 
maleylacetoacetate isomerase activity  
maleylpyruvate isomerase activity 
microtubule plus end polymerase  
microtubule-severing ATPase activity  
palmitoyl-(protein) hydrolase activity  
peptidase activity +   
peptide alpha-N-propionyltransferase activity 
peptide-aspartate beta-dioxygenase activity  
peptide-O-fucosyltransferase activity  
peptide-tryptophan 2,3-dioxygenase activity 
peptidyl-arginine 3-dioxygenase activity 
peptidyl-asparagine 3-dioxygenase activity  
peptidyl-aspartic acid 3-dioxygenase activity  
peptidyl-cysteine S-nitrosylase activity  
peptidyl-histidine dioxygenase activity  
peptidyl-lysine 3-dioxygenase activity 
peptidyl-lysine 4-dioxygenase activity 
peptidyl-lysine 5-dioxygenase activity +   
peptidyl-lysine N6-palmitoyltransferase activity 
peptidyl-proline dioxygenase activity +   
peptidyl-prolyl cis-trans isomerase activity  
Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
peptidylamidoglycolate lyase activity  
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity 
phosphoprotein phosphatase activity +   
polypeptide N-acetylgalactosaminyltransferase activity  
procollagen galactosyltransferase activity  
procollagen glucosyltransferase activity  
protein adenylylhydrolase activity  
protein ADP-ribosylase activity  
protein deacetylase activity +   
protein deglycase activity  
protein demethylase activity +   
protein disulfide isomerase activity  
protein kinase activity +   
protein methylesterase activity +   
protein methylthiotransferase activity 
protein methyltransferase activity +   
protein N-acetylglucosaminyltransferase activity  
protein O-GlcNAc transferase activity  
protein prenyltransferase activity +   
protein xylosyltransferase activity  
protein-cysteine S-acyltransferase activity +   
protein-fructosamine 3-kinase activity  
protein-glucosylgalactosylhydroxylysine glucosidase activity  
protein-glutamic acid ligase activity +   
protein-glycine ligase activity +   
protein-lysine 6-oxidase activity  
protein-ribulosamine 3-kinase activity  
protein-tyrosine sulfotransferase activity  
retinal isomerase activity  
retinol isomerase activity  
Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity 
trans-geranyl-CoA isomerase activity 
transferase activity, transferring amino-acyl groups +   
tubulin-tyrosine ligase activity  
ubiquitin-like protein transferase activity +   
ubiquitinyl hydrolase activity +   

Synonyms
Exact Synonyms: cis-trans proline isomerase activity
Narrow Synonyms: FK506-sensitive peptidyl-prolyl cis-trans isomerase ;   cyclophilin-type peptidyl-prolyl cis-trans isomerase activity ;   juglone-sensitive cis-trans proline isomerase activity ;   juglone-sensitive peptidyl-prolyl cis-trans isomerase activity
Related Synonyms: PPIase activity ;   cyclophilin activity ;   immunophilin ;   parvulin ;   peptide bond isomerase activity ;   peptidyl-prolyl isomerase B reaction ;   peptidylproline cis-trans-isomerase activity ;   peptidylprolyl cis-trans isomerase activity ;   peptidylprolyl isomerase activity ;   rotamase activity
Alternate IDs: GO:0004752 ;   GO:0042028
Xrefs: EC:5.2.1.8 ;   MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN ;   RHEA:16237 ;   reactome:R-HSA-2022073 "Procollagen triple helix formation" ;   reactome:R-HSA-9626816 "PIN1 binds p-S345-NCF1"
Definition Sources: EC:5.2.1.8

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.