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Term:
tubulin-tyrosine ligase activity (GO:0004835)
Annotations: Rat: (2) Mouse: (2) Human: (2) Chinchilla: (2) Bonobo: (2) Dog: (2) Squirrel: (2) Pig: (2)
Parent Terms Term With Siblings Child Terms
2,3-dihydroxybenzoate-serine ligase activity 
4-aminobenzoate amino acid synthetase activity 
4-hydroxybenzoate amino acid synthetase activity 
[acyl-carrier-protein] phosphodiesterase activity 
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase 
[protein-PII] uridylyltransferase activity 
aerobactin synthase activity 
aliphatic aldoxime dehydratase activity 
alpha-1,4-glucan-protein synthase (ADP-forming) activity 
amino acid ligation activity by nonribosomal peptide synthase 
benzoate amino acid synthetase activity 
biotin-protein ligase activity +   
carnitine-CoA ligase activity 
carnosine synthase activity  
catalytic activity, acting on a glycoprotein +   
coenzyme F420-0 gamma-glutamyl ligase activity 
coenzyme F420-0:L-glutamate ligase activity 
coenzyme F420-1:gamma-L-glutamate ligase activity 
coenzyme F420-2 alpha-glutamyl ligase activity 
cyanophycin synthetase activity +  
cyclo-acetoacetyl-L-tryptophan synthetase activity 
D-alanine-alanyl-poly(glycerolphosphate) ligase activity 
D-alanine-D-alanine ligase activity 
deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity 
dihydrofolate synthase activity 
dihydrolipoyllysine-residue acetyltransferase activity  
dihydrolipoyllysine-residue succinyltransferase activity  
gamma-glutamylhistamine synthase activity 
glutamate-cysteine ligase activity  
glutathione synthase activity  
homocarnosine synthase activity  
homoglutathione synthase activity 
indole-3-acetic acid amido synthetase activity +  
jasmonate-amino synthetase activity 
L-amino-acid alpha-ligase activity 
L-propargylglycine--L-glutamate ligase activity 
lipoate-protein ligase activity  
microtubule plus end polymerase  
microtubule-severing ATPase activity  
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity 
palmitoyl-(protein) hydrolase activity  
pantoate-beta-alanine ligase activity 
peptidase activity +   
peptide alpha-N-propionyltransferase activity 
peptide-aspartate beta-dioxygenase activity  
peptide-O-fucosyltransferase activity  
peptide-tryptophan 2,3-dioxygenase activity 
peptidyl-arginine 3-dioxygenase activity 
peptidyl-asparagine 3-dioxygenase activity  
peptidyl-aspartic acid 3-dioxygenase activity  
peptidyl-cysteine S-nitrosylase activity  
peptidyl-histidine dioxygenase activity  
peptidyl-lysine 3-dioxygenase activity 
peptidyl-lysine 4-dioxygenase activity 
peptidyl-lysine 5-dioxygenase activity +   
peptidyl-lysine N6-palmitoyltransferase activity 
peptidyl-proline dioxygenase activity +   
peptidyl-prolyl cis-trans isomerase activity  
peptidylamidoglycolate lyase activity  
phenylacetaldoxime dehydratase activity 
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity 
phosphopantothenate--cysteine ligase activity  
phosphoprotein phosphatase activity +   
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity  
polypeptide N-acetylgalactosaminyltransferase activity  
procollagen galactosyltransferase activity  
procollagen glucosyltransferase activity  
protein adenylylhydrolase activity  
protein ADP-ribosylase activity  
protein deacetylase activity +   
protein deglycase activity  
protein demethylase activity +   
protein disulfide isomerase activity  
protein kinase activity +   
protein methylesterase activity +   
protein methylthiotransferase activity 
protein methyltransferase activity +   
protein N-acetylglucosaminyltransferase activity  
protein O-GlcNAc transferase activity  
protein prenyltransferase activity +   
protein xylosyltransferase activity  
protein-cysteine S-acyltransferase activity +   
protein-fructosamine 3-kinase activity  
protein-glucosylgalactosylhydroxylysine glucosidase activity  
protein-glutamic acid ligase activity +   
protein-glycine ligase activity +   
protein-lysine 6-oxidase activity  
protein-ribulosamine 3-kinase activity  
protein-tyrosine sulfotransferase activity  
Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity 
tetrahydrofolylpolyglutamate synthase activity  
transferase activity, transferring amino-acyl groups +   
tubulin-tyrosine ligase activity  
Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.
tyrosine-arginine ligase activity 
ubiquitin-like protein transferase activity +   
ubiquitinyl hydrolase activity +   
UDP-N-acetylmuramate-L-alanine ligase activity 
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity 
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity 
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity 
UDP-N-acetylmuramoylalanine-D-glutamate ligase activity 
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity 
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity 
vanillate amino acid synthetase activity 

Synonyms
Exact Synonyms: tubulinyl-tyrosine ligase activity
Related Synonyms: TTL activity ;   alpha-tubulin:L-tyrosine ligase (ADP-forming)
Xrefs: EC:6.3.2.25 ;   MetaCyc:6.3.2.25-RXN ;   RHEA:17605 ;   reactome:R-HSA-8955706 "TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin"
Definition Sources: EC:6.3.2.25

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.