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Ontology Browser

Term:
DNA replication initiation (GO:0006270)
Annotations: Rat: (28) Mouse: (32) Human: (43) Chinchilla: (11) Bonobo: (11) Dog: (30) Squirrel: (11) Pig: (29)
Parent Terms Term With Siblings Child Terms
base-excision repair, AP site formation +   
base-excision repair, base-free sugar-phosphate removal  
base-excision repair, gap-filling  
cell cycle DNA replication +   
DNA biosynthetic process +   
DNA catabolic process +   
DNA double-strand break processing +   
DNA excision +   
DNA integration +   
DNA ligation +   
DNA modification +   
DNA protection  
DNA recombination +   
DNA repair +   
DNA replication initiation +   
The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
DNA replication termination +   
DNA replication, Okazaki fragment processing +   
DNA replication, removal of RNA primer +   
DNA replication, synthesis of RNA primer +   
DNA strand elongation +   
DNA strand elongation involved in DNA replication +   
DNA strand renaturation +   
DNA strand resection involved in replication fork processing +   
DNA topological change  
DNA unwinding involved in DNA replication +   
DNA-dependent DNA replication DNA ligation +  
DNA-dependent DNA replication maintenance of fidelity +   
establishment of imprinting at mating-type locus +   
formation of extrachromosomal circular DNA +   
G-quadruplex DNA formation  
gap filling involved in double-strand break repair via nonhomologous end joining 
genetic imprinting at mating-type locus +   
heteroduplex formation +  
lagging strand initiation 
maintenance of DNA methylation  
maintenance of DNA repeat elements +   
maintenance of imprinting at mating-type locus  
mitochondrial DNA metabolic process +   
mitochondrial DNA replication +   
negative regulation of DNA metabolic process +   
negative regulation of DNA-dependent DNA replication +   
nucleotide-excision repair, DNA gap filling  
plastid DNA metabolic process +  
plastid DNA replication 
positive regulation of DNA metabolic process +   
positive regulation of DNA-dependent DNA replication +   
pre-replicative complex assembly +   
programmed DNA elimination +   
R-loop disassembly  
regulation of DNA metabolic process +   
regulation of DNA-dependent DNA replication +   
removal of nonhomologous ends +   
resolution of recombination intermediates +   
rolling circle DNA replication 
strand displacement +   
strand invasion +   
telomere maintenance +   
theta DNA replication 

Synonyms
Exact Synonyms: DNA-dependent DNA replication initiation
Narrow Synonyms: DNA endoreduplication initiation ;   DNA re-replication initiation
Alternate IDs: GO:0042024
Definition Sources: ISBN:071673706X, ISBN:0815316194, PMID:28209641

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.