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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
base-excision repair, AP site formation +   
base-excision repair, base-free sugar-phosphate removal  
base-excision repair, gap-filling  
DNA biosynthetic process +   
DNA catabolic process +   
DNA damage checkpoint +   
DNA damage induced protein phosphorylation  
DNA damage response, detection of DNA damage +   
DNA double-strand break processing +   
DNA excision +   
DNA integration +   
DNA ligation +   
DNA modification +   
DNA protection  
DNA recombination +   
DNA repair +   
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
DNA replication initiation +   
DNA replication termination +   
DNA replication, Okazaki fragment processing +   
DNA replication, removal of RNA primer +   
DNA replication, synthesis of RNA primer +   
DNA strand elongation +   
DNA strand renaturation +   
DNA strand resection involved in replication fork processing +   
DNA topological change  
DNA-dependent DNA replication maintenance of fidelity +   
establishment of imprinting at mating-type locus +   
formation of extrachromosomal circular DNA +   
G-quadruplex DNA formation  
gap filling involved in double-strand break repair via nonhomologous end joining 
genetic imprinting at mating-type locus +   
heteroduplex formation +  
histone H3-K56 acetylation in response to DNA damage 
histone H4 acetylation involved in response to DNA damage stimulus +  
intrinsic apoptotic signaling pathway in response to DNA damage +   
lagging strand initiation 
maintenance of DNA methylation  
maintenance of DNA repeat elements +   
maintenance of imprinting at mating-type locus  
mitochondrial DNA metabolic process +   
negative regulation of DNA metabolic process +   
negative regulation of response to DNA damage stimulus +   
nucleotide-excision repair, DNA gap filling  
plastid DNA metabolic process +  
positive regulation of DNA metabolic process +   
positive regulation of response to DNA damage stimulus +   
programmed DNA elimination +   
R-loop disassembly  
regulation of DNA metabolic process +   
regulation of response to DNA damage stimulus +   
regulation of transcription from RNA polymerase II promoter in response to DNA damage  
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage +   
removal of nonhomologous ends +   
resolution of recombination intermediates +   
signal transduction in response to DNA damage +   
SOS response 
strand displacement +   
strand invasion +   
telomere maintenance +   
telomere maintenance in response to DNA damage +   

Synonyms
Xrefs: Wikipedia:DNA_repair
Definition Sources: PMID:11563486

paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.