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Ontology Browser

Term:
negative regulation of protein kinase activity (GO:0006469)
Annotations: Rat: (222) Mouse: (197) Human: (228) Chinchilla: (220) Bonobo: (220) Dog: (116) Squirrel: (6) Pig: (167)
Parent Terms Term With Siblings Child Terms
negative regulation of diacylglycerol kinase activity 
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation  
negative regulation of hexokinase activity +   
negative regulation of histone phosphorylation +   
negative regulation of I-kappaB phosphorylation  
negative regulation of inhibitory G protein-coupled receptor phosphorylation 
negative regulation of lipid kinase activity +   
negative regulation of MAPK cascade +   
negative regulation of NAD+ kinase activity 
negative regulation of pathway-restricted SMAD protein phosphorylation  
negative regulation of peptidyl-serine phosphorylation +   
negative regulation of peptidyl-threonine phosphorylation  
negative regulation of peptidyl-tyrosine phosphorylation +   
negative regulation of phosphorylation of RNA polymerase II C-terminal domain +  
negative regulation of protein autophosphorylation +   
negative regulation of protein kinase activity +   
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
positive regulation of protein kinase activity +   
regulation of activation of Janus kinase activity +   
regulation of cyclin-dependent protein kinase activity +   
regulation of protein histidine kinase activity +  
regulation of protein serine/threonine kinase activity +   
regulation of protein tyrosine kinase activity +   
regulation of tau-protein kinase activity +   
suppression by virus of host protein phosphorylation +  

Synonyms
Exact Synonyms: down regulation of protein kinase activity ;   downregulation of protein kinase activity
Narrow Synonyms: inhibition of protein kinase activity
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.