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Ontology Browser

Term:
membrane protein ectodomain proteolysis (GO:0006509)
Annotations: Rat: (49) Mouse: (48) Human: (49) Chinchilla: (44) Bonobo: (44) Dog: (46) Squirrel: (44) Pig: (48)
Parent Terms Term With Siblings Child Terms
membrane protein ectodomain proteolysis +   
The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
membrane protein intracellular domain proteolysis +   
membrane protein proteolysis involved in retrograde protein transport, ER to cytosol  

Synonyms
Exact Synonyms: ectodomain cleavage
Broad Synonyms: ectoderm shedding
Related Synonyms: membrane protein solubilization ;   receptor shedding
Definition Sources: GOC:jl, http://www.copewithcytokines.de/

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.