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Ontology Browser

Term:
posttranslational protein targeting to endoplasmic reticulum membrane (GO:0006620)
Annotations: Rat: (12) Mouse: (15) Human: (12) Chinchilla: (11) Bonobo: (12) Dog: (10) Squirrel: (1) Pig: (11)
Parent Terms Term With Siblings Child Terms
cotranslational protein targeting to membrane +   
negative regulation of protein targeting to membrane +   
positive regulation of protein targeting to membrane +   
posttranslational protein targeting to endoplasmic reticulum membrane +   
The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
protein import into chloroplast thylakoid membrane 
protein import into peroxisome membrane  
protein targeting to vacuolar membrane +   
regulation of protein targeting to membrane +   
SRP-dependent cotranslational protein targeting to membrane +   

Synonyms
Exact Synonyms: SRP-independent endoplasmic reticulum protein-membrane targeting ;   posttranslational endoplasmic reticulum membrane targeting ;   posttranslational endoplasmic reticulum protein-membrane targeting ;   posttranslational protein targeting to ER membrane
Definition Sources: ISBN:0716731363

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.