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Ontology Browser

Term:
complement activation, classical pathway (GO:0006958)
Annotations: Rat: (128) Mouse: (161) Human: (160) Chinchilla: (25) Bonobo: (31) Dog: (11) Squirrel: (28) Pig: (15)
Parent Terms Term With Siblings Child Terms
activation of membrane attack complex +   
complement activation, alternative pathway +   
complement activation, classical pathway +   
Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
complement activation, lectin pathway +   
negative regulation of complement activation +   
negative regulation of humoral immune response mediated by circulating immunoglobulin +   
positive regulation of complement activation +   
positive regulation of humoral immune response mediated by circulating immunoglobulin +   
regulation of complement activation +   
regulation of humoral immune response mediated by circulating immunoglobulin +   

Synonyms
Exact Synonyms: complement cascade, classical pathway
Definition Sources: GOC:add, ISBN:0781735149

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.