Ontology Browser

Term:
metaphase/anaphase transition of mitotic cell cycle (GO:0007091)
Annotations: Rat: (53) Mouse: (55) Human: (57) Chinchilla: (54) Bonobo: (56) Dog: (56) Squirrel: (55)
Parent Terms Term With Siblings Child Terms
exit from mitosis +   
G1/S transition of mitotic cell cycle +   
G2/M transition of mitotic cell cycle +   
metaphase/anaphase transition of meiotic cell cycle +   
metaphase/anaphase transition of mitotic cell cycle +   
The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
negative regulation of metaphase/anaphase transition of cell cycle +   
negative regulation of mitotic cell cycle phase transition +   
negative regulation of mitotic sister chromatid separation +   
positive regulation of metaphase/anaphase transition of cell cycle +   
positive regulation of mitotic cell cycle phase transition +   
positive regulation of mitotic sister chromatid separation +   
regulation of metaphase/anaphase transition of cell cycle +   
regulation of mitotic cell cycle phase transition +   
regulation of mitotic metaphase/anaphase transition +   
regulation of mitotic sister chromatid arm separation +  

Synonyms
Exact Synonyms: metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process ;   mitotic metaphase/anaphase transition
Definition Sources: GOC:mtg_cell_cycle, PMID:10465783

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.