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Ontology Browser

Term:
cell surface receptor signaling pathway (GO:0007166)
Annotations: Rat: (2522) Mouse: (2572) Human: (3110) Chinchilla: (2701) Bonobo: (2813) Dog: (1090) Squirrel: (57) Pig: (830)
Parent Terms Term With Siblings Child Terms
apoptotic signaling pathway +   
bile acid signaling pathway +   
calmodulin dependent kinase signaling pathway +   
carbohydrate mediated signaling +   
cell surface receptor signaling pathway +   
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
chloroplast-nucleus signaling pathway 
defense response signaling pathway, resistance gene-dependent 
defense response signaling pathway, resistance gene-independent 
endoplasmic reticulum unfolded protein response +   
ER-nucleus signaling pathway +   
extracellular ATP signaling 
G protein-coupled receptor signaling pathway +   
hormone-mediated signaling pathway +   
hydrogen peroxide mediated signaling pathway +  
hypoxia-inducible factor-1alpha signaling pathway +   
immune response-regulating signaling pathway +   
intracellular receptor signaling pathway +   
intracellular signal transduction +   
ligand-gated ion channel signaling pathway +  
lipoprotein particle mediated signaling +   
mitochondria-nucleus signaling pathway  
necroptotic signaling pathway  
negative regulation of signal transduction +   
neuronal signal transduction +   
osmosensory signaling pathway +   
peptidoglycan recognition protein signaling pathway +  
phototransduction +   
positive regulation of signal transduction +   
postsynaptic signal transduction +   
presynaptic signal transduction +   
red or far-red light signaling pathway +   
regulation of blood pressure by chemoreceptor signaling pathway 
regulation of floral organ abscission by signal transduction +  
regulation of signal transduction +   
salicylic acid mediated signaling pathway +  
signal transduction by conformational transition 
signal transduction by protein phosphorylation +   
signal transduction in absence of ligand +   
signal transduction involved in cellular response to ammonium ion +   
signal transduction involved in filamentous growth 
signal transduction involved in morphogenesis checkpoint 
signal transduction involved in positive regulation of conjugation with cellular fusion +  
signal transduction involved in regulation of aerobic respiration  
signal transduction involved in regulation of gene expression  
SMAD protein signal transduction +   
sphingolipid mediated signaling pathway +   

Synonyms
Exact Synonyms: cell surface receptor linked signal transduction ;   cell surface receptor linked signaling pathway ;   cell surface receptor linked signalling pathway
Xrefs: MIPS_funcat:30.05
Definition Sources: GOC:bf, GOC:mah, GOC:pr, GOC:signaling

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.