Ontology Browser

Term:
chemical synaptic transmission (GO:0007268)
Annotations: Rat: (848) Mouse: (852) Human: (710) Chinchilla: (660) Bonobo: (681) Dog: (684) Squirrel: (667)
Parent Terms Term With Siblings Child Terms
anterograde trans-synaptic signaling by nitric oxide 
anterograde trans-synaptic signaling by trans-synaptic protein complex 
chemical synaptic transmission +   
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.

Synonyms
Exact Synonyms: signal transmission across a synapse
Broad Synonyms: synaptic transmission
Related Synonyms: neurotransmission
Xrefs: Wikipedia:Neurotransmission
Definition Sources: GOC:jl, MeSH:D009435

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.