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palmitoyl-(protein) hydrolase activity (GO:0008474)
Annotations: Rat: (17) Mouse: (14) Human: (15) Chinchilla: (9) Bonobo: (9) Dog: (14) Squirrel: (9) Pig: (14)
Parent Terms Term With Siblings Child Terms
2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity 
2-oxoglutaryl-CoA thioesterase activity 
3-isopropylbut-3-enoyl-CoA thioesterase activity 
3-oxo-dodecanoyl-ACP hydrolase activity 
3-oxo-myristoyl-ACP hydrolase activity 
3-oxo-myristoyl-CoA hydrolase activity 
3-oxo-palmitoyl-ACP hydrolase activity 
3-oxoacyl-CoA hydrolase activity 
[acyl-carrier-protein] phosphodiesterase activity 
[citrate-(pro-3S)-lyase] thiolesterase activity 
[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase 
[protein-PII] uridylyltransferase activity 
acyl-[acyl-carrier-protein] hydrolase activity +   
alpha-1,4-glucan-protein synthase (ADP-forming) activity 
biotin-protein ligase activity +   
catalytic activity, acting on a glycoprotein +   
CoA hydrolase activity +   
deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity 
dihydrolipoyllysine-residue acetyltransferase activity  
dihydrolipoyllysine-residue succinyltransferase activity  
glutathione thiolesterase activity 
hydroxyacylglutathione hydrolase activity  
lipoate-protein ligase activity  
microtubule plus end polymerase  
microtubule-severing ATPase activity  
myristoyl-CoA hydrolase activity  
palmitoyl-(protein) hydrolase activity  
Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.
peptidase activity +   
peptide alpha-N-propionyltransferase activity 
peptide-aspartate beta-dioxygenase activity  
peptide-O-fucosyltransferase activity  
peptide-tryptophan 2,3-dioxygenase activity 
peptidyl-arginine 3-dioxygenase activity 
peptidyl-asparagine 3-dioxygenase activity  
peptidyl-aspartic acid 3-dioxygenase activity  
peptidyl-cysteine S-nitrosylase activity  
peptidyl-histidine dioxygenase activity  
peptidyl-lysine 3-dioxygenase activity 
peptidyl-lysine 4-dioxygenase activity 
peptidyl-lysine 5-dioxygenase activity +   
peptidyl-lysine N6-palmitoyltransferase activity 
peptidyl-proline dioxygenase activity +   
peptidyl-prolyl cis-trans isomerase activity  
peptidylamidoglycolate lyase activity  
phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity 
phosphoprotein phosphatase activity +   
polypeptide N-acetylgalactosaminyltransferase activity  
procollagen galactosyltransferase activity  
procollagen glucosyltransferase activity  
protein adenylylhydrolase activity  
protein ADP-ribosylase activity  
protein deacetylase activity +   
protein deglycase activity  
protein demethylase activity +   
protein disulfide isomerase activity  
protein kinase activity +   
protein methylesterase activity +   
protein methylthiotransferase activity 
protein methyltransferase activity +   
protein N-acetylglucosaminyltransferase activity  
protein O-GlcNAc transferase activity  
protein prenyltransferase activity +   
protein xylosyltransferase activity  
protein-cysteine S-acyltransferase activity +   
protein-fructosamine 3-kinase activity  
protein-glucosylgalactosylhydroxylysine glucosidase activity  
protein-glutamic acid ligase activity +   
protein-glycine ligase activity +   
protein-lysine 6-oxidase activity  
protein-ribulosamine 3-kinase activity  
protein-tyrosine sulfotransferase activity  
S-formylglutathione hydrolase activity  
S-succinylglutathione hydrolase activity 
Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity 
transferase activity, transferring amino-acyl groups +   
tubulin-tyrosine ligase activity  
ubiquitin-like protein transferase activity +   
ubiquitinyl hydrolase activity +   

Exact Synonyms: palmitoyl-protein thioesterase activity ;   palmitoyl-protein thiolesterase activity
Broad Synonyms: palmitoyl-[protein] hydrolase
Xrefs: EC: ;   MetaCyc: ;   RHEA:19233 ;   Reactome:R-HSA-9647994 "RAS proteins are depalmitoylated" ;   reactome:R-HSA-203613 "depalmitoylation of eNOS" ;   reactome:R-HSA-5690517 "PPT1 hydrolyses palmitoylated proteins" ;   reactome:R-HSA-8933328 "LYPLA2 hydrolyses PALM-C3,4-GAP43"
Definition Sources: EC:

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.