Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

procollagen-lysine 5-dioxygenase activity (GO:0008475)
Annotations: Rat: (3) Mouse: (3) Human: (3) Chinchilla: (3) Bonobo: (3) Dog: (3) Squirrel: (3) Pig: (3)
Parent Terms Term With Siblings Child Terms
procollagen-lysine 5-dioxygenase activity  
Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.

Broad Synonyms: lysine hydroxylase activity ;   lysine,2-oxoglutarate 5-dioxygenase activity ;   lysine-2-oxoglutarate dioxygenase activity ;   lysyl hydroxylase activity
Related Synonyms: collagen lysine hydroxylase activity ;   lysylprotocollagen dioxygenase activity ;   procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating) ;   procollagen-lysine,2-oxoglutarate 5-dioxygenase activity ;   protocollagen lysine dioxygenase activity ;   protocollagen lysine hydroxylase activity ;   protocollagen lysyl hydroxylase activity
Xrefs: EC: ;   MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN ;   RHEA:16569 ;   reactome:R-HSA-1981104 "Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines"
Definition Sources: EC:

paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.