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Ontology Browser

Term:
N-glycan processing to lysosome (GO:0016256)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (0) Pig: (1)
Parent Terms Term With Siblings Child Terms
Golgi apparatus mannose trimming  
N-glycan diversification 
N-glycan processing to lysosome  
The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.
N-glycan processing to secreted and cell-surface N-glycans 
protein targeting to lysosome involved in chaperone-mediated autophagy  

Synonyms
Definition Sources: ISBN:0879695595

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.