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Term:
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702)
Annotations: Rat: (27) Mouse: (28) Human: (27) Chinchilla: (26) Bonobo: (26) Dog: (26) Squirrel: (0) Pig: (24)
Parent Terms Term With Siblings Child Terms
1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity 
1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity 
1,2-dihydroxy-8-methylnaphthalene dioxygenase activity 
1,2-dihydroxynaphthalene dioxygenase activity 
2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity 
2,4,5-trichlorophenoxyacetic acid oxygenase activity 
2-oxoglutarate-dependent dioxygenase activity +   
3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity 
3-butenylglucosinolate 2-hydroxylase activity 
alpha-ketoglutarate-dependent xanthine dioxygenase activity 
DDT 2,3-dioxygenase activity 
DOPA dioxygenase activity 
inositol oxygenase activity  
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor +   
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) +  
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen +   
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
tryptophan 2'-dioxygenase activity 

Synonyms
Xrefs: EC:1.13.11 ;   reactome:R-HSA-2161775 "ALOX12 oxidises LTA4 to LXA4/B4" ;   reactome:R-HSA-2161907 "ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4" ;   reactome:R-HSA-2161917 "ALOX5 oxidises 15S-HpETE to LXA4/B4" ;   reactome:R-HSA-5164399 "BCO2:Fe2+ cleaves betaC to APO10al and bION" ;   reactome:R-HSA-9018880 "Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE" ;   reactome:R-HSA-9020274 "ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA" ;   reactome:R-HSA-9026408 "PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3" ;   reactome:R-HSA-9026918 "Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA"
Definition Sources: GOC:mah

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.