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nucleoside-triphosphatase activity (GO:0017111)
Annotations: Rat: (783) Mouse: (743) Human: (825) Chinchilla: (738) Bonobo: (765) Dog: (676) Squirrel: (5) Pig: (663)
Parent Terms Term With Siblings Child Terms
4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity 
5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity 
adenosine-tetraphosphatase activity 
ADP-ribose diphosphatase activity  
ADP-sugar diphosphatase activity +   
CDP-diacylglycerol diphosphatase activity 
CDP-glycerol diphosphatase activity  
CoA pyrophosphatase activity 
deoxynucleoside-diphosphatase activity +  
diacylglycerol diphosphate phosphatase activity  
dihydroneopterin triphosphate pyrophosphohydrolase activity 
diphosphoinositol-polyphosphate diphosphatase activity  
dolichyldiphosphatase activity  
endopolyphosphatase activity  
exopolyphosphatase activity  
GDP-mannose hydrolase activity  
guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity  
inorganic diphosphatase activity  
inositol bisdiphosphate tetrakisphosphate diphosphatase activity +   
inositol diphosphate pentakisphosphate diphosphatase activity +   
inositol diphosphate tetrakisphosphate diphosphatase activity +   
m7G(5')pppN diphosphatase activity  
nucleoside-diphosphatase activity +   
nucleoside-triphosphatase activity +   
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
nucleoside-triphosphate diphosphatase activity +   
nucleotide diphosphatase activity +   
oligosaccharide-diphosphodolichol diphosphatase activity 
phosphoribosyl-ATP diphosphatase activity 
RNA pyrophosphohydrolase activity  
triphosphatase activity  
UDP-2,3-diacylglucosamine hydrolase activity 
UDP-sugar diphosphatase activity  
undecaprenyl-diphosphatase activity 

Exact Synonyms: NTPase activity ;   nucleoside 5-triphosphatase activity ;   nucleoside triphosphate hydrolase activity ;   nucleoside triphosphate phosphohydrolase activity ;   nucleoside-5-triphosphate phosphohydrolase activity ;   unspecific diphosphate phosphohydrolase activity
Broad Synonyms: apyrase activity
Xrefs: EC: ;   MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN ;   RHEA:23680 ;   reactome:R-HSA-8850846 "NTPDase1 hydrolyzes nucleoside triphosphates" ;   reactome:R-HSA-8851089 "NTPDase2 hydrolyzes nucleoside triphosphates" ;   reactome:R-HSA-8851110 "NTPDase3 hydrolyzes nucleoside triphosphates" ;   reactome:R-HSA-8851234 "NTPDase4 hydrolyzes nucleoside triphosphates" ;   reactome:R-HSA-8851494 "NTPDase7 hydrolyzes nucleoside triphosphates" ;   reactome:R-HSA-8851538 "NTPDase8 hydrolyzes nucleoside triphosphates"
Definition Sources: EC:

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.