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Term:
peptidyl-diphthamide biosynthetic process from peptidyl-histidine (GO:0017183)
Annotations: Rat: (6) Mouse: (6) Human: (8) Chinchilla: (7) Bonobo: (8) Dog: (5) Squirrel: (0) Pig: (6)
Parent Terms Term With Siblings Child Terms
aldehyde biosynthetic process +   
alkane biosynthetic process +  
alkene biosynthetic process +  
alkyne biosynthetic process +  
androgen biosynthetic process +   
antibiotic biosynthetic process +   
aromatic compound biosynthetic process +   
auxin biosynthetic process +  
C21-steroid hormone biosynthetic process +   
cellular alcohol biosynthetic process +   
cellular carbohydrate biosynthetic process +   
cellular macromolecule biosynthetic process +   
cellular nitrogen compound biosynthetic process +   
cofactor biosynthetic process +   
cytokinin biosynthetic process +   
estrogen biosynthetic process +   
glycerol ether biosynthetic process +   
glycerolipid biosynthetic process +   
heterocycle biosynthetic process +   
isoprenoid biosynthetic process +   
ketone biosynthetic process +   
ketone body biosynthetic process +   
membrane lipid biosynthetic process +   
mucilage biosynthetic process +  
negative regulation of cellular biosynthetic process +   
negative regulation of cytoplasmic translational elongation +   
neurotransmitter biosynthetic process +   
neutral lipid biosynthetic process +   
organic acid biosynthetic process +   
organic phosphonate biosynthetic process 
organomercury biosynthetic process +  
peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine +  
peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine 
peptidyl-diphthamide biosynthetic process from peptidyl-histidine  
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
peptidyl-diphthamide catabolic process 
peptidyl-diphthine biosynthetic process from peptidyl-histidine 
peptidyl-thyronine biosynthetic process from peptidyl-tyrosine 
pheromone biosynthetic process +  
phospholipid biosynthetic process +   
polyphosphate biosynthetic process 
positive regulation of cellular biosynthetic process +   
positive regulation of cytoplasmic translational elongation +  
regulation of cellular biosynthetic process +   
regulation of cytoplasmic translational elongation through polyproline stretches +  
regulation of cytoplasmic translational fidelity  
rhodopsin biosynthetic process 
sulfur compound biosynthetic process +   
toxin biosynthetic process +   
vitamin biosynthetic process +   

Synonyms
Exact Synonyms: peptidyl-diphthamide anabolism from peptidyl-histidine ;   peptidyl-diphthamide formation from peptidyl-histidine ;   peptidyl-diphthamide synthesis from peptidyl-histidine
Xrefs: RESID:AA0040
Definition Sources: GOC:pde, PMID:20559380, RESID:AA0040

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.