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Ontology Browser

Term:
peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase (GO:0017186)
Annotations: Rat: (2) Mouse: (2) Human: (2) Chinchilla: (2) Bonobo: (2) Dog: (2) Squirrel: (2) Pig: (2)
Parent Terms Term With Siblings Child Terms
C-terminal peptidyl-glutamine amidation 
isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine  
N-terminal peptidyl-glutamine acetylation 
N-terminal peptidyl-glutamine methylation 
peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine 
peptide cross-linking via S-(L-isoglutamyl)-L-cysteine 
peptidyl-glutamine esterification +  
peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine +  
peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine 
peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase  
The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.

Synonyms
Exact Synonyms: 2-pyrrolidone-5-carboxylic acid biosynthesis ;   2-pyrrolidone-5-carboxylic acid biosynthetic process ;   peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase ;   peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase ;   peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase
Xrefs: RESID:AA0031
Definition Sources: RESID:AA0031

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.