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Term:
second-messenger-mediated signaling (GO:0019932)
Annotations: Rat: (465) Mouse: (429) Human: (449) Chinchilla: (404) Bonobo: (427) Dog: (428) Squirrel: (415) Pig: (436)
Parent Terms Term With Siblings Child Terms
cytoplasmic pattern recognition receptor signaling pathway +   
endosomal signal transduction 
hippo signaling +   
I-kappaB kinase/NF-kappaB signaling +   
inositol lipid-mediated signaling +   
intracellular signal transduction involved in positive regulation of cell growth 
intrinsic apoptotic signaling pathway +   
MAPK cascade +   
negative regulation of intracellular signal transduction +   
NIK/NF-kappaB signaling +   
phosphorelay signal transduction system +   
PKR signal transduction 
positive regulation of intracellular signal transduction +   
protein kinase A signaling +   
protein kinase B signaling +   
protein kinase C signaling +   
protein kinase D signaling +   
regulation of intracellular signal transduction +   
second-messenger-mediated signaling +   
Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.
signal transduction by p53 class mediator +   
signal transduction downstream of smoothened +   
signal transduction in response to DNA damage +   
signal transduction involved in cell cycle checkpoint +   
signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 
small GTPase mediated signal transduction +   
stress-activated protein kinase signaling cascade +   
TOR signaling +   
TRAF-mediated signal transduction 

Synonyms
Exact Synonyms: second messenger mediated signalling ;   second-messenger-mediated signal transduction
Xrefs: MIPS_funcat:30.01.09
Definition Sources: GOC:signaling, ISBN:0815316194, PMID:15221855, Wikipedia:Second_messenger_system

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.