Ontology Browser

Term:
midbrain-hindbrain boundary initiation (GO:0021547)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1)
Parent Terms Term With Siblings Child Terms
adaxial/abaxial pattern specification +   
adenohypophysis formation 
adrenal cortex formation  
aerenchyma formation 
amelogenesis +   
amnioserosa formation 
angiogenesis +   
angiogenic sprout fusion +   
animal organ formation +   
anterior neural plate formation +  
anterior/posterior pattern specification +   
anther wall tapetum formation +  
apical ectodermal ridge formation +  
arthrospore formation 
beak formation 
blastocyst formation +   
blood microparticle formation +   
bud field specification 
canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation +   
cardiac chamber formation +   
cellular component assembly involved in morphogenesis +   
cellularization +   
central nervous system formation 
centrolateral pattern formation +  
cephalic furrow formation 
cerebellar cortex formation +   
cerebellar granular layer formation +   
cerebellar molecular layer formation +   
cerebellar Purkinje cell layer formation +   
cerebellum formation  
cerebral cortex regionalization  
chorion micropyle formation 
chorion-containing eggshell pattern formation 
cranial nerve formation +   
cuticle pattern formation +  
dentinogenesis +   
dorsal appendage formation 
dorsal motor nucleus of vagus nerve formation +  
dorsal/ventral pattern formation +   
ectodermal placode formation +   
eggshell formation +  
embryonic camera-type eye formation +   
endocardial cushion formation +   
endocardium formation  
fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation +   
floor plate formation  
floral whorl formation 
flower formation 
forebrain induction by the anterior neural ridge 
forebrain regionalization +   
forebrain-midbrain boundary formation  
formation of anatomical boundary +   
formation of animal organ boundary +   
formation of infection structure on or near host +  
formation of primary germ layer +   
formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction +  
fungiform papilla formation  
ganglion formation +  
germarium-derived egg chamber formation +  
germinal center formation +   
ground tissue pattern formation 
heart rudiment formation +  
heart valve formation +   
hindbrain formation +   
hypophysis formation 
imaginal disc pattern formation +  
imaginal disc-derived wing vein specification +  
inferior olivary nucleus formation 
kidney rudiment formation +   
labyrinthine layer formation 
lamina terminalis formation 
layer formation in cerebral cortex +   
leaflet formation +  
left/right pattern formation +   
limb bud formation +   
limb epidermis stratification +  
locus ceruleus formation 
lung lobe formation  
lymphangiogenesis +   
mammary gland bud formation +   
mammary gland formation +   
medulla oblongata formation +  
metanephric cap formation +  
midbrain-hindbrain boundary initiation  
The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
midbrain-hindbrain boundary maturation +   
midbrain-hindbrain boundary morphogenesis +   
negative regulation of anterior neural cell fate commitment of the neural plate +  
neural crest formation +   
neural fold elevation formation  
neural fold formation +   
neural fold hinge point formation 
neural keel formation 
neural plate formation +   
neural plate regionalization +   
neural rod formation +  
neural tube patterning +   
neurohypophysis formation 
nipple sheath formation  
notochord formation  
optic cup formation involved in camera-type eye development  
optic vesicle formation 
otolith formation +   
periodic partitioning +  
petal epidermis patterning 
plant organ formation +  
platelet formation +   
pons formation +  
posterior neural plate formation +  
prechordal plate formation  
primitive streak formation +   
proximal/distal pattern formation +   
R8 cell-mediated photoreceptor organization 
radial pattern formation +   
regionalization involved in semicircular canal formation 
renal capsule formation +   
renal capsule specification +   
renal vesicle formation +   
reproductive blastospore formation 
retina layer formation +   
retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation 
rhombomere formation +   
roof plate formation  
segmentation +   
selective angioblast sprouting +  
somitogenesis +   
specification of animal organ identity +   
specification of animal organ position  
specification of ovule identity 
specification of plant organ identity +  
specification of plant organ number +  
specification of plant organ position 
Spemann organizer formation +   
spinal cord patterning +   
sporulation resulting in formation of a cellular spore +  
stomatal complex formation 
stomatal complex patterning +  
submandibular salivary gland formation  
superior olivary nucleus formation 
syncytium formation +   
taste bud formation 
telencephalon regionalization +   
tendon formation +   
trabecula formation +   
tracheal pit formation in open tracheal system 
tracheoesophageal septum formation  
transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation 
trichome patterning +  
tripartite regional subdivision +   
tube formation +   
ventral furrow formation +  
ventral midline determination  
vertebrate eye-specific patterning  
wing and notum subfield formation +  
xylem and phloem pattern formation +  

Synonyms
Exact Synonyms: MHB biosynthesis ;   MHB formation ;   midbrain-hindbrain boundary biosynthesis ;   midbrain-hindbrain boundary formation
Related Synonyms: isthmus biosynthesis ;   isthmus formation
Definition Sources: GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, GOC:mtg_15jun06, PMID:15541513

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.