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Ontology Browser

Term:
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification (GO:0021776)
Annotations: Rat: (3) Mouse: (3) Human: (3) Chinchilla: (3) Bonobo: (3) Dog: (3) Squirrel: (0) Pig: (3)
Parent Terms Term With Siblings Child Terms
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning  
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification  
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification  
The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
smoothened signaling pathway involved in ventral spinal cord interneuron specification  

Synonyms
Exact Synonyms: hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification ;   hh signaling pathway involved in spinal cord motor neuron cell fate specification ;   smoothened signalling pathway involved in spinal cord motor neuron cell fate specification
Definition Sources: GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06, PMID:15936325

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.