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Ontology Browser

Term:
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021914)
Annotations: Rat: (4) Mouse: (4) Human: (4) Chinchilla: (4) Bonobo: (4) Dog: (4) Squirrel: (0) Pig: (3)
Parent Terms Term With Siblings Child Terms
BMP signaling pathway involved in spinal cord dorsal/ventral patterning  
negative regulation of anterior neural cell fate commitment of the neural plate +  
negative regulation of branching morphogenesis of a nerve  
negative regulation of cell proliferation in midbrain  
negative regulation of cerebellar granule cell precursor proliferation +   
negative regulation of convergent extension involved in rhombomere morphogenesis 
negative regulation of formation of radial glial scaffolds 
negative regulation of hh target transcription factor activity  
negative regulation of myelination  
negative regulation of neurogenesis +   
negative regulation of optic nerve formation 
negative regulation of planar cell polarity pathway involved in neural tube closure  
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning  
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning  
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.
negative regulation of synapse assembly +   
negative regulation of synapse maturation  
retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning +  
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification  
smoothened signaling pathway involved in ventral spinal cord interneuron specification  
smoothened signaling pathway involved in ventral spinal cord patterning +   
ventral spinal cord interneuron fate commitment +   

Synonyms
Exact Synonyms: down regulation of smoothened signaling pathway in ventral spinal cord patterning ;   downregulation of smoothened signaling pathway in ventral spinal cord patterning ;   negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning ;   negative regulation of hh signaling pathway involved in ventral spinal cord patterning ;   negative regulation of smoothened signalling pathway in ventral spinal cord patterning
Narrow Synonyms: inhibition of smoothened signaling pathway in ventral spinal cord patterning
Definition Sources: GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mtg_15jun06, GOC:tb, PMID:11262869

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.