Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
secretory granule +     
acrosomal vesicle +   
azurophil granule +   
chromaffin granule +   
cortical granule  
dense core granule +   
ficolin-1-rich granule +   
insulin-responsive compartment  
lamellar body +   
mucin granule  
mucocyst 
platelet alpha granule +   
A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
platelet dense granule +   
secretory granule lumen +   
secretory granule membrane +   
specific granule +   
tertiary granule +   
Weibel-Palade body  
zymogen granule +   

Synonyms
Xrefs: Wikipedia:Platelet_alpha-granule
Definition Sources: PMID:8467233

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.