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Term:
stress-activated protein kinase signaling cascade (GO:0031098)
Annotations: Rat: (287) Mouse: (287) Human: (329) Chinchilla: (252) Bonobo: (257) Dog: (274) Squirrel: (256) Pig: (275)
Parent Terms Term With Siblings Child Terms
cellular detoxification of nitrogen compound  
cellular response to anoxia  
cellular response to caloric restriction  
cellular response to cell envelope stress 
cellular response to chemical stress +   
cellular response to cold +   
cellular response to DNA damage stimulus +   
cellular response to fluid shear stress +   
cellular response to heat +   
cellular response to hypoxia +   
cellular response to immobilization stress  
cellular response to isolation stress 
cellular response to starvation +   
cellular response to sterol depletion +   
cellular response to topologically incorrect protein +   
cellular response to water deprivation +   
cellular senescence +   
cellular stress response to acid chemical  
cytoplasmic pattern recognition receptor signaling pathway +   
defense response by cell wall thickening +  
DNA protection  
endosomal signal transduction 
hippo signaling +   
I-kappaB kinase/NF-kappaB signaling +   
inositol lipid-mediated signaling +   
integrated stress response signaling +   
intracellular signal transduction involved in positive regulation of cell growth 
intrinsic apoptotic signaling pathway +   
MAPK cascade +   
negative regulation of intracellular signal transduction +   
negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress 
neuron projection regeneration +   
NIK/NF-kappaB signaling +   
phosphorelay signal transduction system +   
PKR-mediated signaling 
plant-type hypersensitive response +  
positive regulation of intracellular signal transduction +   
priming of cellular response to stress 
protein kinase A signaling +   
protein kinase B signaling +   
protein kinase C signaling +   
protein kinase D signaling +   
RAM/MOR signaling pathway 
regulation of cellular response to stress +   
regulation of DNA-templated transcription in response to stress +   
regulation of intracellular signal transduction +   
regulation of mRNA stability involved in response to stress +   
regulation of translation in response to stress +   
response to endoplasmic reticulum stress +   
response to mitochondrial depolarisation +   
second-messenger-mediated signaling +   
signal transduction by p53 class mediator +   
signal transduction downstream of smoothened +   
signal transduction in response to DNA damage +   
signal transduction involved in cell cycle checkpoint +   
signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 
small GTPase mediated signal transduction +   
stress-activated protein kinase signaling cascade +   
A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
stress-induced homeostatically regulated protein degradation pathway 
stress-induced mitochondrial fusion  
TOR signaling +   
TRAF-mediated signal transduction  
trehalose metabolism in response to stress +   

Synonyms
Exact Synonyms: SAPK signaling pathway ;   SAPK signalling pathway ;   stress-activated protein kinase signaling pathway ;   stress-activated protein kinase signalling pathway
Narrow Synonyms: JNK signaling pathway ;   JNK signalling pathway
Definition Sources: GOC:mah

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.