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Ontology Browser

pericentric heterochromatin assembly (GO:0031508)
Annotations: Rat: (7) Mouse: (5) Human: (6) Chinchilla: (5) Bonobo: (5) Dog: (6) Squirrel: (5) Pig: (6)
Parent Terms Term With Siblings Child Terms
CENP-A containing nucleosome assembly +   
DNA methylation-dependent heterochromatin assembly +   
gene silencing +   
heterochromatin assembly by small RNA +   
heterochromatin domain assembly +  
heterochromatin island assembly +  
inactivation of X chromosome by heterochromatin assembly  
kinetochore assembly +   
mRNA catabolic process +   
negative regulation of cytokine production +   
negative regulation of gene expression, epigenetic +   
negative regulation of heterochromatin assembly +   
negative regulation of histone gene expression 
negative regulation of mRNA processing +   
negative regulation of production of miRNAs involved in gene silencing by miRNA +   
negative regulation of production of siRNA involved in RNA interference  
negative regulation of protein maturation +   
negative regulation of rhodopsin gene expression 
negative regulation of RNA splicing +   
negative regulation of rRNA processing  
negative regulation of snoRNA processing 
negative regulation of transcription, DNA-templated +   
negative regulation of translation +   
negative regulation of tRNA processing 
pericentric heterochromatin assembly +   
The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA.
positive regulation of heterochromatin assembly +   
rDNA heterochromatin assembly +   
regulation of centromere complex assembly +   
regulation of heterochromatin assembly +   
senescence-associated heterochromatin focus assembly  
silent mating-type cassette heterochromatin assembly +  
subtelomeric heterochromatin assembly +   
suppression by virus of host gene expression +  

Exact Synonyms: centromere chromatin silencing ;   centromeric heterochromatin biosynthesis ;   centromeric heterochromatin formation ;   centromeric silencing ;   chromatin silencing at centromere ;   heterochromatic silencing at centromere
Narrow Synonyms: chromatin silencing at centromere outer repeat region
Related Synonyms: centric heterochromatin formation ;   chromatin silencing at pericentric region
Alternate IDs: GO:0030702 ;   GO:1990141
Definition Sources: GOC:mah, PMID:20206496, PMID:22729156

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.