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Term:
negative regulation of GTPase activity (GO:0034260)
Annotations: Rat: (38) Mouse: (31) Human: (48) Chinchilla: (45) Bonobo: (44) Dog: (45) Squirrel: (45)
Parent Terms Term With Siblings Child Terms
negative regulation of 3'-UTR-mediated mRNA stabilization 
negative regulation of action potential +   
negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 
negative regulation of arginase activity 
negative regulation of asexual reproduction +  
negative regulation of ATPase activity +   
negative regulation of behavior +   
negative regulation of beta-galactosidase activity  
negative regulation of cell killing +   
negative regulation of cellular process +   
negative regulation of cellular protein localization +   
negative regulation of circadian rhythm +   
negative regulation of cohesin unloading 
negative regulation of cyclic-nucleotide phosphodiesterase activity  
negative regulation of cytokine activity +   
negative regulation of deacetylase activity +   
negative regulation of developmental pigmentation +   
negative regulation of developmental process +   
negative regulation of DNA N-glycosylase activity 
negative regulation of DNA-binding transcription factor activity +   
negative regulation of dosage compensation by inactivation of X chromosome 
negative regulation of dUTP diphosphatase activity 
negative regulation of endo-1,4-beta-xylanase activity 
negative regulation of establishment of protein localization +   
negative regulation of establishment of RNA localization to telomere  
negative regulation of exo-alpha-sialidase activity +   
negative regulation of fibrinolysis  
negative regulation of glucosylceramidase activity 
negative regulation of growth +   
negative regulation of growth hormone activity 
negative regulation of GTP cyclohydrolase I activity  
negative regulation of GTPase activity  
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
negative regulation of guanyl-nucleotide exchange factor activity +   
negative regulation of helicase activity +   
negative regulation of hemostasis +   
negative regulation of immune system process +   
negative regulation of interphase mitotic telomere clustering 
negative regulation of intracellular mRNA localization +  
negative regulation of lipase activity +   
negative regulation of lipid localization +   
negative regulation of locomotion +   
negative regulation of long-term synaptic depression  
negative regulation of long-term synaptic potentiation  
negative regulation of lysozyme activity 
negative regulation of maintenance of permeability of blood-brain barrier  
negative regulation of membrane depolarization +   
negative regulation of membrane hyperpolarization  
negative regulation of metabolic process +   
negative regulation of microfilament motor activity +  
negative regulation of microtubule motor activity +   
negative regulation of mitotic telomere tethering at nuclear periphery 
negative regulation of multi-organism process +   
negative regulation of multicellular organismal process +   
negative regulation of nitrogen utilization +  
negative regulation of nuclear receptor transcription coactivator activity  
negative regulation of nuclease activity +   
negative regulation of peptidase activity +   
negative regulation of phosphatase activity +   
negative regulation of phosphorus utilization 
negative regulation of proteasome-activating ATPase activity 
negative regulation of protein localization to cell-cell adherens junction 
negative regulation of protein localization to presynapse 
negative regulation of receptor localization to synapse  
negative regulation of reproductive process +   
negative regulation of response to stimulus +   
negative regulation of ribonucleoprotein complex localization +  
negative regulation of short-term synaptic potentiation  
negative regulation of signaling +   
negative regulation of sulfur utilization 
negative regulation of telomerase RNA localization to Cajal body 
negative regulation of transport +   
positive regulation of GTPase activity +   

Synonyms
Exact Synonyms: down regulation of GTPase activity ;   downregulation of GTPase activity ;   negative regulation of guanosinetriphosphatase activity
Narrow Synonyms: down regulation of Rab GTPase activity ;   down regulation of Ras GTPase activity ;   down regulation of Rho GTPase activity ;   down regulation of regulation of Ran GTPase activity ;   downregulation of Rab GTPase activity ;   downregulation of Ras GTPase activity ;   downregulation of Rho GTPase activity ;   downregulation of regulation of Ran GTPase activity ;   inhibition of GTPase activity ;   inhibition of Rab GTPase activity ;   inhibition of Ras GTPase activity ;   inhibition of Rho GTPase activity ;   inhibition of regulation of Ran GTPase activity ;   negative regulation of Rab GTPase activity ;   negative regulation of Ran GTPase activity ;   negative regulation of Ras GTPase activity ;   negative regulation of Rho GTPase activity
Alternate IDs: GO:0034259 ;   GO:0034261 ;   GO:1902264 ;   GO:1902881
Definition Sources: GO_REF:0000058, GOC:mah, GOC:rb, GOC:TermGenie, PMID:16143306, PMID:24335649

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