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Ontology Browser

Term:
centromere complex assembly (GO:0034508)
Annotations: Rat: (29) Mouse: (29) Human: (58) Chinchilla: (17) Bonobo: (16) Dog: (28) Squirrel: (17) Pig: (27)
Parent Terms Term With Siblings Child Terms
centromere complex assembly +   
The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
chromatin organization +   
chromosome breakage  
chromosome decondensation +  
chromosome organization involved in meiotic cell cycle +   
DNA conformation change +   
DNA recombinase assembly +   
DNA replication preinitiation complex assembly +   
dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome 
dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome 
dsDNA loop formation +   
heterochromatin assembly +   
heterochromatin maintenance  
kinetochore organization +   
maintenance of DNA repeat elements +   
negative regulation of chromosome organization +   
nucleosome assembly +   
nucleotide-excision repair, DNA damage recognition +   
nucleotide-excision repair, preincision complex assembly  
polytene chromosome puffing +  
positive regulation of chromosome organization +   
pre-replicative complex assembly +   
protein-DNA ISRE complex assembly 
regulation of chromosome organization +   
shelterin complex assembly +   
sister chromatid cohesion +   
sister chromatid segregation +   
synaptonemal complex organization +   
telomere organization +   
telomere-telomerase complex assembly 
transcription preinitiation complex assembly +   
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery +   
tRNA gene clustering 

Synonyms
Exact Synonyms: centromere assembly ;   centromere organization ;   chromosome, centromeric region assembly
Definition Sources: GOC:mah, GOC:vw

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.