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Ontology Browser

Term:
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872)
Annotations: Rat: (17) Mouse: (18) Human: (40) Chinchilla: (15) Bonobo: (16) Dog: (16) Squirrel: (16) Pig: (14)
Parent Terms Term With Siblings Child Terms
blue light signaling pathway  
cytoplasmic pattern recognition receptor signaling pathway +   
intracellular bile acid receptor signaling pathway  
intracellular endosomal pattern recognition receptor signaling pathway 
intracellular steroid hormone receptor signaling pathway +   
juvenile hormone mediated signaling pathway 
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway +   
A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process.
peroxisome proliferator activated receptor signaling pathway +   
retinoic acid receptor signaling pathway +   
thyroid hormone mediated signaling pathway +   
vitamin D receptor signaling pathway +   

Synonyms
Exact Synonyms: NLR signaling pathway ;   nucleotide-binding domain, leucine rich repeat containing receptor signal transduction ;   nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway ;   nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway
Related Synonyms: NOD-like receptor signaling pathway
Definition Sources: GOC:sj, PMID:18280719, Reactome:168643

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.