Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Parent Terms Term With Siblings Child Terms
DNA duplex unwinding +   
DNA rewinding  
The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.
DNA strand renaturation +   
G-quadruplex DNA unwinding +   

Narrow Synonyms: RPA-dependent DNA rewinding ;   single-stranded DNA bubble rewinding
Related Synonyms: DNA annealing
Definition Sources: PMID:21078962, PMID:22704558, PMID:22705370, PMID:22759634

paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.