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Term:
calcitriol biosynthetic process from calciol (GO:0036378)
Annotations: Rat: (4) Mouse: (3) Human: (4) Chinchilla: (3) Bonobo: (3) Dog: (3) Squirrel: (3) Pig: (3)
Parent Terms Term With Siblings Child Terms
1,3-dichloro-2-propanol biosynthetic process 
1,5-anhydro-D-fructose biosynthetic process 
2-deoxystreptamine biosynthetic process 
alditol biosynthetic process +   
butirosin biosynthetic process 
calcitriol biosynthetic process from calciol  
Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.
diol biosynthetic process +   
ergosterol biosynthetic process +   
gentamycin biosynthetic process 
inositol biosynthetic process +   
inositol phosphate biosynthetic process +   
kanamycin biosynthetic process 
negative regulation of vitamin D biosynthetic process +   
neomycin biosynthetic process 
paromomycin biosynthetic process 
phenolic phthiocerol biosynthetic process 
phytosphingosine biosynthetic process  
positive regulation of vitamin D biosynthetic process +   
regulation of vitamin D biosynthetic process +   
streptomycin biosynthetic process 
tobramycin biosynthetic process 
vitamin D3 biosynthetic process 
vitamin D3 catabolic process 

Synonyms
Exact Synonyms: calcitriol biosynthesis from calciol ;   vitamin D3 activation
Broad Synonyms: 1alpha,25(OH)2D3 biosynthesis ;   1alpha,25-dihydroxycholecalciferol biosynthesis ;   1alpha,25-dihydroxyvitamin D3 biosynthesis
Definition Sources: GOC:BHF, GOC:rl, PMID:17426122, PMID:20511049

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.