Ontology Browser

Term:
cytoplasmic pattern recognition receptor signaling pathway in response to virus (GO:0039528)
Annotations: Rat: (24) Mouse: (23) Human: (28) Chinchilla: (27) Bonobo: (27) Dog: (26) Squirrel: (27)
Parent Terms Term With Siblings Child Terms
aggregation involved in sorocarp development +  
biofilm formation +   
cellular process regulating host cell cycle in response to virus  
conjugation +  
cytolysis in other organism +   
cytoplasmic pattern recognition receptor signaling pathway in response to virus +   
Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
genetic transfer +  
maintenance of stationary phase +  
melanization defense response +  
multi-organism cell wall macromolecule metabolic process +   
multi-organism membrane organization +   
multi-organism organelle organization 
multi-organism plasmodesmata-mediated intercellular transport 
myxococcal fruiting body development 
negative regulation of defense response to virus +   
nucleotide-binding oligomerization domain containing signaling pathway +   
phage shock 
phenotypic switching in response to host 
plant-type hypersensitive response +  
positive regulation by virus of host cytokine production 
positive regulation of chemokine production +   
positive regulation of connective tissue growth factor production +   
positive regulation of cytokine biosynthetic process +   
positive regulation of cytokine production involved in immune response +   
positive regulation of cytokine production involved in inflammatory response  
positive regulation of cytokine secretion +   
positive regulation of fibroblast growth factor production  
positive regulation of granulocyte macrophage colony-stimulating factor production +   
positive regulation of hepatocyte growth factor production +  
positive regulation of interferon-gamma production +   
positive regulation of interleukin-1 production +   
positive regulation of interleukin-10 production +   
positive regulation of interleukin-11 production +  
positive regulation of interleukin-12 production +   
positive regulation of interleukin-13 production +   
positive regulation of interleukin-14 production +  
positive regulation of interleukin-15 production +   
positive regulation of interleukin-16 production +  
positive regulation of interleukin-17 production +   
positive regulation of interleukin-18 production +   
positive regulation of interleukin-19 production +  
positive regulation of interleukin-2 production +   
positive regulation of interleukin-20 production +  
positive regulation of interleukin-21 production +  
positive regulation of interleukin-22 production +  
positive regulation of interleukin-23 production +   
positive regulation of interleukin-24 production +  
positive regulation of interleukin-25 production +  
positive regulation of interleukin-26 production +  
positive regulation of interleukin-27 production +  
positive regulation of interleukin-3 production +   
positive regulation of interleukin-35 production +  
positive regulation of interleukin-4 production +   
positive regulation of interleukin-5 production +   
positive regulation of interleukin-6 production +   
positive regulation of interleukin-7 production +  
positive regulation of interleukin-8 production +   
positive regulation of interleukin-9 production +  
positive regulation of macrophage colony-stimulating factor production +   
positive regulation of MDA-5 signaling pathway  
positive regulation of platelet-derived growth factor production  
positive regulation of RIG-I signaling pathway  
positive regulation of transforming growth factor beta production +   
positive regulation of tumor necrosis factor superfamily cytokine production +   
positive regulation of type I interferon production +   
positive regulation of type III interferon production  
positive regulation of vascular endothelial growth factor production  
quorum sensing +   
regulation of defense response to virus +   
suppression by virus of host cell lysis in response to superinfection 
virus induced gene silencing +  

Synonyms
Exact Synonyms: cytoplasmic pattern recognition receptor signalling pathway in response to virus ;   virus-induced cytoplasmic pattern recognition receptor signaling pathway
Narrow Synonyms: RIG-I-like receptor (RLR) signaling pathway ;   RIG-I/MDA5 signaling pathway ;   RIG-like helicase signaling pathway ;   RIG-like receptor signaling pathway ;   RLH signaling pathway ;   RLR signaling pathway ;   cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway
Definition Sources: GOC:bf, PMID:17328678, PMID:18272355, PMID:19531363

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.