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Ontology Browser

negative regulation of RIG-I signaling pathway (GO:0039536)
Annotations: Rat: (8) Mouse: (8) Human: (8) Chinchilla: (8) Bonobo: (8) Dog: (8) Squirrel: (8) Pig: (8)
Parent Terms Term With Siblings Child Terms
negative regulation of MDA-5 signaling pathway  
negative regulation of RIG-I signaling pathway  
Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
positive regulation of RIG-I signaling pathway  
regulation of RIG-I signaling pathway +   

Exact Synonyms: negative regulation of DDX58 signaling pathway ;   negative regulation of RIG-I signalling pathway ;   negative regulation of retinoic acid inducible gene I signaling pathway
Definition Sources: GOC:bf, GOC:jl

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.