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Term:
negative regulation of cytokine biosynthetic process (GO:0042036)
Annotations: Rat: (31) Mouse: (31) Human: (31) Chinchilla: (29) Bonobo: (30) Dog: (13) Squirrel: (1) Pig: (21)
Parent Terms Term With Siblings Child Terms
chemokine biosynthetic process +   
connective tissue growth factor biosynthetic process +   
cytokine biosynthetic process involved in immune response +  
granulocyte macrophage colony-stimulating factor biosynthetic process +   
hepatocyte growth factor biosynthetic process +   
interferon-gamma biosynthetic process +   
interleukin-1 biosynthetic process +   
interleukin-10 biosynthetic process +   
interleukin-11 biosynthetic process +  
interleukin-12 biosynthetic process +   
interleukin-13 biosynthetic process +   
interleukin-14 biosynthetic process +  
interleukin-15 biosynthetic process +  
interleukin-16 biosynthetic process +  
interleukin-17 biosynthetic process +   
interleukin-18 biosynthetic process +   
interleukin-19 biosynthetic process +  
interleukin-2 biosynthetic process +   
interleukin-20 biosynthetic process +  
interleukin-21 biosynthetic process +  
interleukin-22 biosynthetic process +  
interleukin-23 biosynthetic process +  
interleukin-24 biosynthetic process +  
interleukin-26 biosynthetic process +  
interleukin-27 biosynthetic process +  
interleukin-3 biosynthetic process +   
interleukin-35 biosynthetic process +  
interleukin-4 biosynthetic process +   
interleukin-5 biosynthetic process +   
interleukin-6 biosynthetic process +   
interleukin-7 biosynthetic process +  
interleukin-8 biosynthetic process +   
interleukin-9 biosynthetic process +  
lymphotoxin A biosynthetic process +   
negative regulation of (+)-kotanin biosynthetic process 
negative regulation of (R)-mevalonic acid biosynthetic process 
negative regulation of 17-methylnonadec-1-ene biosynthetic process 
negative regulation of 18-methylnonadec-1-ene biosynthetic process 
negative regulation of abscisic acid biosynthetic process 
negative regulation of aflatoxin biosynthetic process 
negative regulation of alkane biosynthetic process +  
negative regulation of amyloid fibril formation  
negative regulation of amyloid precursor protein catabolic process +   
negative regulation of antimicrobial peptide biosynthetic process +  
negative regulation of asperthecin biosynthetic process 
negative regulation of bile acid biosynthetic process  
negative regulation of brevianamide F biosynthetic process 
negative regulation of carotenoid biosynthetic process 
negative regulation of cellular amino acid biosynthetic process +   
negative regulation of cellular macromolecule biosynthetic process +   
negative regulation of cellular protein metabolic process +   
negative regulation of chemokine production +   
negative regulation of connective tissue growth factor production +  
negative regulation of cordyol C biosynthetic process 
negative regulation of cutin biosynthetic process 
negative regulation of cytokine biosynthetic process +   
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.
negative regulation of cytokine production involved in immune response +   
negative regulation of cytokine production involved in inflammatory response  
negative regulation of cytokine secretion +   
negative regulation of demethylkotanin biosynthetic process 
negative regulation of diacylglycerol biosynthetic process 
negative regulation of diorcinol biosynthetic process 
negative regulation of dopamine biosynthetic process 
negative regulation of emericellamide biosynthetic process +  
negative regulation of emodin biosynthetic process 
negative regulation of endocrocin biosynthetic process 
negative regulation of ent-pimara-8(14),15-diene biosynthetic process 
negative regulation of ergosterol biosynthetic process 
negative regulation of ergot alkaloid biosynthetic process +  
negative regulation of fatty acid biosynthetic process +   
negative regulation of fibroblast growth factor production  
negative regulation of fumagillin biosynthetic process 
negative regulation of fumitremorgin B biosynthetic process 
negative regulation of fumonisin biosynthetic process 
negative regulation of gerfelin biosynthetic process 
negative regulation of gliotoxin biosynthetic process 
negative regulation of gluconeogenesis  
negative regulation of glutathione biosynthetic process 
negative regulation of glycoprotein metabolic process +   
negative regulation of granulocyte macrophage colony-stimulating factor production +   
negative regulation of helvolic acid biosynthetic process 
negative regulation of hemoglobin biosynthetic process  
negative regulation of hepatocyte growth factor production +   
negative regulation of hexadecanal biosynthetic process 
negative regulation of hormone biosynthetic process +   
negative regulation of hyaluronan biosynthetic process  
negative regulation of hydrogen peroxide biosynthetic process  
negative regulation of hydrogen sulfide biosynthetic process 
negative regulation of immunoglobulin biosynthetic process 
negative regulation of inositol biosynthetic process 
negative regulation of inositol phosphate biosynthetic process +   
negative regulation of integrin biosynthetic process +   
negative regulation of interferon-gamma production +   
negative regulation of interleukin-1 production +   
negative regulation of interleukin-10 production +   
negative regulation of interleukin-11 production +  
negative regulation of interleukin-12 production +   
negative regulation of interleukin-13 production +   
negative regulation of interleukin-14 production +  
negative regulation of interleukin-15 production +  
negative regulation of interleukin-16 production +  
negative regulation of interleukin-17 production +   
negative regulation of interleukin-18 production +   
negative regulation of interleukin-19 production +  
negative regulation of interleukin-2 production +   
negative regulation of interleukin-20 production +  
negative regulation of interleukin-21 production +  
negative regulation of interleukin-22 production +  
negative regulation of interleukin-23 production +   
negative regulation of interleukin-24 production +  
negative regulation of interleukin-25 production +  
negative regulation of interleukin-26 production +  
negative regulation of interleukin-27 production +  
negative regulation of interleukin-3 production +   
negative regulation of interleukin-35 production +  
negative regulation of interleukin-4 production +   
negative regulation of interleukin-5 production +   
negative regulation of interleukin-6 production +   
negative regulation of interleukin-7 production +  
negative regulation of interleukin-8 production +   
negative regulation of interleukin-9 production +  
negative regulation of iron-sulfur cluster assembly +  
negative regulation of iron-sulfur-molybdenum cofactor assembly 
negative regulation of isoprene biosynthetic process 
negative regulation of kojic acid biosynthetic process 
negative regulation of L-ascorbic acid biosynthetic process 
negative regulation of lactose biosynthetic process 
negative regulation of lipoprotein metabolic process +   
negative regulation of low-density lipoprotein particle receptor biosynthetic process  
negative regulation of macrophage colony-stimulating factor production +   
negative regulation of melanin biosynthetic process  
negative regulation of methanofuran biosynthetic process 
negative regulation of methanophenazine biosynthetic process 
negative regulation of MHC class I biosynthetic process 
negative regulation of MHC class II biosynthetic process  
negative regulation of monodictyphenone biosynthetic process 
negative regulation of naphtho-gamma-pyrone biosynthetic process 
negative regulation of nitric oxide biosynthetic process  
negative regulation of nitric-oxide synthase biosynthetic process  
negative regulation of nonadec-1-ene biosynthetic process 
negative regulation of nucleotide biosynthetic process +   
negative regulation of nucleotide catabolic process +  
negative regulation of o-orsellinic acid biosynthetic process 
negative regulation of octadecene biosynthetic process 
negative regulation of orcinol biosynthetic process 
negative regulation of penicillin biosynthetic process 
negative regulation of pentose catabolic process to ethanol +  
negative regulation of phenazine biosynthetic process 
negative regulation of phospholipid biosynthetic process +   
negative regulation of phytoalexin biosynthetic process 
negative regulation of polyketide biosynthetic process +  
negative regulation of protein activation cascade +   
negative regulation of protein catabolic process +   
negative regulation of protein maturation +   
negative regulation of pseurotin A biosynthetic process 
negative regulation of quinolinate biosynthetic process  
negative regulation of receptor biosynthetic process +   
negative regulation of retinoic acid biosynthetic process  
negative regulation of RNA biosynthetic process +   
negative regulation of sarcinapterin biosynthetic process 
negative regulation of serotonin biosynthetic process 
negative regulation of siderophore biosynthetic process +  
negative regulation of sinapate ester biosynthetic process 
negative regulation of spermidine biosynthetic process 
negative regulation of sphingolipid biosynthetic process +   
negative regulation of sterigmatocystin biosynthetic process 
negative regulation of syringal lignin biosynthetic process 
negative regulation of tatiopterin biosynthetic process 
negative regulation of tensidol A biosynthetic process 
negative regulation of tensidol B biosynthetic process 
negative regulation of terrequinone A biosynthetic process 
negative regulation of tetrapyrrole biosynthetic process +  
negative regulation of thiamine biosynthetic process 
negative regulation of thiamine diphosphate biosynthetic process 
negative regulation of thymidylate synthase biosynthetic process  
negative regulation of TRAIL receptor 1 biosynthetic process 
negative regulation of TRAIL receptor 2 biosynthetic process 
negative regulation of transforming growth factor beta production +   
negative regulation of triglyceride biosynthetic process +   
negative regulation of trypanothione biosynthetic process 
negative regulation of tumor necrosis factor superfamily cytokine production +   
negative regulation of type I interferon production +   
negative regulation of type III interferon production 
negative regulation of ubiquinone biosynthetic process 
negative regulation of vascular endothelial growth factor production  
negative regulation of violaceol I biosynthetic process 
negative regulation of violaceol II biosynthetic process 
negative regulation of vitamin D biosynthetic process +   
negative regulation of xanthone-containing compound biosynthetic process +  
positive regulation of cytokine biosynthetic process +   
regulation of chemokine biosynthetic process +   
regulation of connective tissue growth factor biosynthetic process +  
regulation of cytokine biosynthetic process +   
regulation of cytokine biosynthetic process involved in immune response +  
regulation of granulocyte macrophage colony-stimulating factor biosynthetic process +   
regulation of hepatocyte growth factor biosynthetic process +   
regulation of interferon-alpha biosynthetic process +   
regulation of interferon-beta biosynthetic process +   
regulation of interferon-gamma biosynthetic process +   
regulation of interleukin-1 biosynthetic process +   
regulation of interleukin-10 biosynthetic process +   
regulation of interleukin-11 biosynthetic process +  
regulation of interleukin-12 biosynthetic process +   
regulation of interleukin-13 biosynthetic process +   
regulation of interleukin-14 biosynthetic process +  
regulation of interleukin-15 biosynthetic process +  
regulation of interleukin-16 biosynthetic process +  
regulation of interleukin-17 biosynthetic process +   
regulation of interleukin-18 biosynthetic process +   
regulation of interleukin-19 biosynthetic process +  
regulation of interleukin-2 biosynthetic process +   
regulation of interleukin-20 biosynthetic process +  
regulation of interleukin-21 biosynthetic process +  
regulation of interleukin-22 biosynthetic process +  
regulation of interleukin-23 biosynthetic process +  
regulation of interleukin-24 biosynthetic process +  
regulation of interleukin-26 biosynthetic process +  
regulation of interleukin-27 biosynthetic process +  
regulation of interleukin-3 biosynthetic process +   
regulation of interleukin-35 biosynthetic process +  
regulation of interleukin-4 biosynthetic process +   
regulation of interleukin-5 biosynthetic process +   
regulation of interleukin-6 biosynthetic process +   
regulation of interleukin-7 biosynthetic process +  
regulation of interleukin-8 biosynthetic process +   
regulation of interleukin-9 biosynthetic process +  
regulation of lymphotoxin A biosynthetic process +   
regulation of TRAIL biosynthetic process +   
regulation of tumor necrosis factor biosynthetic process +   
suppression by virus of host cytokine production +  
TRAIL biosynthetic process +   
tumor necrosis factor biosynthetic process +   
type I interferon biosynthetic process +   

Synonyms
Exact Synonyms: down regulation of cytokine biosynthetic process ;   downregulation of cytokine biosynthetic process ;   negative regulation of cytokine anabolism ;   negative regulation of cytokine biosynthesis ;   negative regulation of cytokine formation ;   negative regulation of cytokine synthesis
Narrow Synonyms: inhibition of cytokine biosynthetic process
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.