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Term:
signal transduction in response to DNA damage (GO:0042770)
Annotations: Rat: (95) Mouse: (95) Human: (138) Chinchilla: (89) Bonobo: (92) Dog: (93) Squirrel: (89) Pig: (96)
Parent Terms Term With Siblings Child Terms
cytoplasmic pattern recognition receptor signaling pathway +   
DNA damage checkpoint +   
DNA damage induced protein phosphorylation  
DNA damage response, detection of DNA damage +   
DNA repair +   
endosomal signal transduction 
hippo signaling +   
histone H3-K56 acetylation in response to DNA damage 
histone H4 acetylation involved in response to DNA damage stimulus +  
I-kappaB kinase/NF-kappaB signaling +   
inositol lipid-mediated signaling +   
intracellular signal transduction involved in positive regulation of cell growth 
intrinsic apoptotic signaling pathway +   
intrinsic apoptotic signaling pathway in response to DNA damage +   
MAPK cascade +   
negative regulation of intracellular signal transduction +   
negative regulation of response to DNA damage stimulus +   
NIK/NF-kappaB signaling +   
phosphorelay signal transduction system +   
PKR-mediated signaling 
positive regulation of intracellular signal transduction +   
positive regulation of response to DNA damage stimulus +   
protein kinase A signaling +   
protein kinase B signaling +   
protein kinase C signaling +   
protein kinase D signaling +   
RAM/MOR signaling pathway 
regulation of intracellular signal transduction +   
regulation of response to DNA damage stimulus +   
regulation of transcription from RNA polymerase II promoter in response to DNA damage  
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage +   
second-messenger-mediated signaling +   
signal transduction by p53 class mediator +   
signal transduction downstream of smoothened +   
signal transduction in response to DNA damage +   
A cascade of processes induced by the detection of DNA damage within a cell.
signal transduction involved in cell cycle checkpoint +   
signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle 
small GTPase mediated signal transduction +   
SOS response 
stress-activated protein kinase signaling cascade +   
telomere maintenance in response to DNA damage +   
TOR signaling +   
TRAF-mediated signal transduction  

Synonyms
Exact Synonyms: DNA damage response, signal transduction ;   response to DNA damage stimulus by intracellular signaling cascade
Definition Sources: GOC:go_curators

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.