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Ontology Browser

Term:
activation of Janus kinase activity (GO:0042976)
Annotations: Rat: (16) Mouse: (14) Human: (15) Chinchilla: (14) Bonobo: (14) Dog: (6) Squirrel: (1) Pig: (9)
Parent Terms Term With Siblings Child Terms
activation of Janus kinase activity +   
The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
activation of MAPK activity +   
activation of MAPKK activity +   
activation of MAPKKK activity +   
activation of NF-kappaB-inducing kinase activity  
activation of protein histidine kinase activity 
activation of protein kinase A activity  
activation of protein kinase B activity  
activation of protein kinase C activity  
activation of transmembrane receptor protein tyrosine kinase activity  
enzyme active site formation via O4'-phospho-L-tyrosine 
histone-tyrosine phosphorylation +   
negative regulation of peptidyl-tyrosine phosphorylation +   
peptidyl-tyrosine autophosphorylation +   
peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity 
positive regulation of activation of Janus kinase activity  
positive regulation of peptidyl-tyrosine phosphorylation +   
positive regulation of tyrosine phosphorylation of STAT protein  
regulation of peptidyl-tyrosine phosphorylation +   
tyrosine phosphorylation of STAT protein +   

Synonyms
Exact Synonyms: activation of JAK protein ;   activation of JAK protein by tyrosine phosphorylation
Narrow Synonyms: activation of JAK1 kinase activity ;   activation of JAK1 protein ;   activation of JAK2 kinase activity ;   activation of JAK2 protein ;   tyrosine phosphorylation of JAK1 protein ;   tyrosine phosphorylation of JAK2 protein
Broad Synonyms: positive regulation of JAK protein activity by tyrosine phosphorylation
Related Synonyms: tyrosine phosphorylation of JAK protein
Alternate IDs: GO:0010531 ;   GO:0042977
Definition Sources: GOC:jl, PMID:12479803

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.