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Term:
negative regulation of DNA-binding transcription factor activity (GO:0043433)
Annotations: Rat: (165) Mouse: (159) Human: (165) Chinchilla: (150) Bonobo: (157) Dog: (154) Squirrel: (156)
Parent Terms Term With Siblings Child Terms
negative regulation of 3'-UTR-mediated mRNA stabilization 
negative regulation of action potential +   
negative regulation of asexual reproduction +  
negative regulation of behavior +   
negative regulation of binding +   
negative regulation of catalytic activity +   
negative regulation of cell killing +   
negative regulation of cellular process +   
negative regulation of cellular protein localization +   
negative regulation of circadian rhythm +   
negative regulation of cohesin unloading 
negative regulation of cytokine activity +   
negative regulation of developmental pigmentation +   
negative regulation of developmental process +   
negative regulation of DNA-binding transcription factor activity +   
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
negative regulation of dosage compensation by inactivation of X chromosome 
negative regulation of establishment of protein localization +   
negative regulation of establishment of RNA localization to telomere  
negative regulation of fibrinolysis  
negative regulation of growth +   
negative regulation of growth hormone activity 
negative regulation of GTPase activity  
negative regulation of guanyl-nucleotide exchange factor activity +   
negative regulation of hemostasis +   
negative regulation of hh target transcription factor activity 
negative regulation of immune system process +   
negative regulation of interphase mitotic telomere clustering 
negative regulation of intracellular mRNA localization +  
negative regulation of lipid localization +   
negative regulation of locomotion +   
negative regulation of long-term synaptic depression  
negative regulation of long-term synaptic potentiation  
negative regulation of low-density lipoprotein receptor activity  
negative regulation of maintenance of permeability of blood-brain barrier  
negative regulation of membrane depolarization +   
negative regulation of membrane hyperpolarization  
negative regulation of metabolic process +   
negative regulation of mitotic telomere tethering at nuclear periphery 
negative regulation of molecular function in other organism +   
negative regulation of molecular function, epigenetic 
negative regulation of multi-organism process +   
negative regulation of multicellular organismal process +   
negative regulation of nitrogen utilization +  
negative regulation of nuclear receptor transcription coactivator activity  
negative regulation of phosphorus utilization 
negative regulation of proteasome-activating ATPase activity 
negative regulation of protein localization to cell-cell adherens junction 
negative regulation of protein localization to presynapse 
negative regulation of receptor localization to synapse  
negative regulation of reproductive process +   
negative regulation of response to stimulus +   
negative regulation of ribonucleoprotein complex localization +  
negative regulation of RNA binding transcription factor activity 
negative regulation of short-term synaptic potentiation  
negative regulation of signaling +   
negative regulation of signaling receptor activity +   
negative regulation of sulfur utilization 
negative regulation of telomerase RNA localization to Cajal body 
negative regulation of transport +   
negative regulation of transporter activity +   
positive regulation of DNA-binding transcription factor activity +   
positive regulation of molecular function in other organism +  

Synonyms
Exact Synonyms: down regulation of transcription factor activity ;   downregulation of transcription factor activity ;   negative regulation of sequence-specific DNA binding transcription factor activity
Narrow Synonyms: inhibition of transcription factor activity ;   negative regulation of androgen receptor activity ;   negative regulation of thyroid hormone receptor activity
Broad Synonyms: negative regulation of transcription factor activity
Alternate IDs: GO:1904168 ;   GO:2000824
Definition Sources: GOC:jl

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